Table 3.
Main grade 3/4 toxicities of apatinib treatment
| Toxicity | Grades 3–4 | Percentage |
|---|---|---|
| Hand–foot syndrome | 6 | 14.3 |
| Hypertension | 4 | 9.5 |
| Proteinuria | 3 | 7.1 |
| Hepatic injure | 3 | 7.1 |
| Fatigue | 2 | 4.8 |
| Nausea/vomiting | 2 | 4.8 |
| Febrile neutropenia | 1 | 2.4 |
| Anemia | 1 | 2.4 |
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