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The role of Src in FAK-regulated migratory and invasive activity of bladder cancer cells.
Notes: T24 and 5637 cells were treated with 10 μM PP2 or siRNA against Src. (A, B, D and E) Expression of Src, pSrc, FAK and pFAK was measured by Western blotting. (C and F) Cell invasion and migration were examined by Transwell assays. Scale bar, 200 μm.
Abbreviations: FAK, focal adhesion kinase; siRNA, small interfering RNA; TGFβ, transforming growth factor beta; conRNA, control RNA.
