Fig 1. Manhattan plot of the differentially methylated CpG sites for READ.

The red dots indicated differentially methylated CpG sites in READ locating on chromosome 2, 4, 6, 8, 10, 12, 14, 16, 18, 20 and 22; the black dots indicated differentially methylated CpG sites in READ locating on chromosome 1, 3, 5, 7, 9, 11, 13, 15, 17, 19 and 21. The purple-horizontal solid line is the significant level (P-value<0.05) for identification of differentially methylated CpG sites.