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. 2017 Mar 28;12(3):e0174780. doi: 10.1371/journal.pone.0174780

Fig 7. NRG1 release and ErbB4 phosphorylation following KA receptor activation in vivo.

Fig 7

(A) Levels of soluble-free NRG1 in the hippocampus were determined in epileptic and control rats. (B) Total ADAM activity in hippocampal tissue lysates as described in Fig 5. (C) Crude hippocampal membranes were subjected to Western blotting using anti-phospho-ErbB4 and anti-ErbB4 antibodies. The mean levels of phospho-ErbB4 and ErbB4 immunoreactivities in controls were defined as 100%. Data represent mean ± SD (four rats per group); *p < 0.05, **p < 0.01, vs. saline-treated control group.