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Enhanced expression and methylation levels of ABCB1 were detected in A549/DDP cells. (a) The expression of ABCB1 in A549 and DDP resistance A549 cells was detected using Western blot. (b) Quantitative analysis results of Western blot. (c) Bisulphite sequencing was performed to detect the methylation levels of ABCB1 downstream promoter in A549 and DDP resistance A549 cells. (d) Methylation sites of ABCB1 gene. **P < 0.01.
