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Effect of compounds A and B on DENV RNA copy number in infected cells. Uninfected and DENV-infected THP-1 (A) or 293T (B) cells were left untreated or treated with compound A or compound B (range: 3–30 μM), or statin (range: 0.3–1 μM) for 72 h. Total RNA was extracted from cell lysates and DENV RNA was detected by RT-qPCR. Results show the mean of two independent experiments. ∗P < 0.05, ∗∗P < 0.01 vs. control (0.2% DMSO; unpaired two-tailed t-test). Data represent mean ± SEM.
