Day 1 |
Prominent ulceration with diffuse burns on the skin and subcutaneous tissue, evidence of coagulative necrosis |
Presence of ulcer on surface due to injury, covered with slough and necrotic debris |
Day 4 |
Beginning of granulation tissue formation with reepithelialization, moderate scab formation, good proliferation, numerous inflammatory macrophages and fibroblasts seen |
Adequate scab formed, beneath which a clot composed of fibrin, RBCs and platelets are formed. Inflammatory cells like macrophages and neutrophils migrate to the site |
Day 8 |
Proliferation of fibroblasts seen with fresh collagen being laid down, angiogenesis, neovascularization, wound contraction seen |
Areas of fibroblast proliferation, new blood vessel formation, wound begin to contract |
Day 12 |
Prominent wound contraction, collagen and fibrosis are increased prominent scar formation, cellularity reduced, all of which suggest good healing process |
Collagen is laid down significantly, inflammatory cells are reduced due to the healing process and presence of fibrous scar is noticed |