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. 2017 Mar 22;13:899–908. doi: 10.2147/NDT.S130855

Table S2.

Association of MIF promoter polymorphisms with suicide completers and controls for females

Polymorphism Female suicide
(n=194)
Female control
(n=388)
P-valuea Global P-valueb OR (95% CI) Power
N Frequency N Frequency
MIF-794CATT5–8
Genotype
 55 30 0.155 56 0.144 0.741 0.850 1.084 (0.670–1.755) 0.066
 56 72 0.371 132 0.340 0.461 1.145 (0.799–1.639) 0.114
 57 24 0.124 51 0.131 0.793 0.933 (0.555–1.568) 0.055
 66 34 0.175 81 0.209 0.339 0.805 (0.517–1.255) 0.162
 67 30 0.155 55 0.142 0.678 1.108 (0.684–1.794) 0.072
 77 4 0.021 13 0.034 0.384 0.607 (0.195–1.888) 0.119
Allele
 CATT5 156 0.402 295 0.380 0.470 0.762 1.096 (0.854–1.407) 0.112
 CATT6 170 0.438 349 0.450 0.708 0.954 (0.746–1.219) 0.067
 CATT7 62 0.160 132 0.170 0.656 0.928 (0.667–1.290) 0.070
MIF-173G/C
Genotype
 GG 121 0.624 233 0.601 0.589 0.390 1.103 (0.774–1.572) 0.082
 GC 67 0.345 135 0.348 0.951 0.989 (0.688–1.420) 0.050
 CC 6 0.031 20 0.052 0.256 0.587 (0.232–1.487) 0.196
Allele
 G 309 0.796 601 0.774 0.394 1.139 (0.845–1.536) 0.089
 C 79 0.204 175 0.226
Haplotype
 MIFCATT5-173G 143.7 0.370 262.6 0.338 0.280 0.519 1.150 (0.892–1.483) 0.187
 MIFCATT6-173G 164.3 0.423 340.6 0.439 0.615 0.939 (0.734–1.201) 0.081
 MIFCATT7-173G 2.1 0.005 1.1 0.001 0.233 3.834 (0.380–38.62) 0.071
 MIFCATT5-173C 12.3 0.032 32.4 0.042 0.398 0.751 (0.385–1.465) 0.124
 MIFCATT6-173C 5.7 0.015 8.4 0.011 0.564 1.362 (0.467–3.975) 0.092
 MIFCATT7-173C 59.9 0.154 130.9 0.169 0.538 0.900 (0.645–1.256) 0.098

Notes:

a

P-values were tested with the χ2 test.

b

Global P-value was calculated by Fisher’s exact test or Cochran–Armitage test for trend, as appropriate.

Abbreviations: MIF, macrophage migration inhibitory factor; OR, odds ratio; CI, confidence interval.