Table S4.

Association of MIF promoter polymorphisms with nonviolent suicide completers and controls

Polymorphism	Nonviolent suicide (n=10)		Control (n=728)		P-valuea	Global P-valueb	OR (95% CI)	Power
	N	Frequency	N	Frequency
MIF-794CATT5–8
Genotype
55	1	0.100	105	0.144	0.692	0.890	0.659 (0.083–5.258)	0.037
56	5	0.500	251	0.345	0.306		1.900 (0.545–6.626)	0.187
57	1	0.100	95	0.130	0.776		0.740 (0.093–5.910)	0.036
66	1	0.100	158	0.217	0.371		0.401 (0.050–3.188)	0.073
67	2	0.200	93	0.128	0.498		1.707 (0.357–8.161)	0.152
77	0	0.000	26	0.036	0.543		–	–
Allele
CATT5	8	0.400	556	0.382	0.868	1.000	1.079 (0.438–2.656)	0.055
CATT6	9	0.450	660	0.453	0.977		0.987 (0.406–2.396)	0.050
CATT7	3	0.150	240	0.165	0.859		0.894 (0.260–3.075)	0.045
MIF-173G/C
Genotype
GG	6	0.600	451	0.620	0.840	0.852	0.921 (0.258–3.294)	0.054
GC	4	0.400	237	0.326	0.874		1.381 (0.386–4.941)	0.089
CC	0	0.000	40	0.055	0.953		–	–
Allele
G	16	0.800	1,139	0.782	0.935		1.113 (0.370–3.353)	0.047
C	4	0.200	317	0.218
Haplotype
MIFCATT5-173G	6.8	0.340	496.6	0.341	0.980	0.971	0.995 (0.392–2.526)	0.050
MIFCATT6-173G	8.9	0.445	641.2	0.440	0.965		1.019 (0.419–2.476)	0.050
MIFCATT7-173G	0.0	0.000	1.0	0.001	0.907		–	–
MIFCATT5-173C	1.2	0.060	59.4	0.041	0.642		1.501 (0.233–9.675)	0.120
MIFCATT6-173C	0.1	0.005	18.8	0.013	0.744		0.384 (0.001–195.1)	0.004
MIFCATT7-173C	3.0	0.150	239.0	0.164	0.863		0.899 (0.261–3.090)	0.045

Notes:

^aP-values were tested with the χ² test.

^bGlobal P-value was calculated by Fisher’s exact test or Cochran–Armitage test for trend, as appropriate.

Abbreviations: MIF, macrophage migration inhibitory factor; OR, odds ratio; CI, confidence interval.