Table S5.

Association of MIF promoter polymorphisms with violent and nonviolent suicide completers

Polymorphism	Violent suicide (n=568)		Nonviolent suicide (n=10)		P-valuea	Global P-valueb	OR (95% CI)	Power
	N	Frequency	N	Frequency
MIF-794CATT5–8
Genotype
55	82	0.144	1	0.100	0.692	0.940	1.519 (0.190–12.15)	0.032
56	220	0.387	5	0.500	0.469		0.632 (0.181–2.209)	0.134
57	70	0.123	1	0.100	0.824		1.265 (0.158–10.13)	0.036
66	105	0.185	1	0.100	0.492		2.041 (0.256–16.29)	0.031
67	79	0.139	2	0.200	0.582		0.646 (0.135–3.099)	0.139
77	12	0.021	0	0.000	0.642		–
Allele
CATT5	454	0.400	8	0.400	0.998	1.000	0.999 (0.405–2.462)	0.050
CATT6	509	0.448	9	0.450	0.986		0.992 (0.408–2.413)	0.050
CATT7	173	0.152	3	0.150	0.978		1.018 (0.295–3.511)	0.049
MIF-173G/C
Genotype
GG	355	0.625	6	0.600	0.871	0.932	1.111 (0.310–3.982)	0.056
GC	190	0.335	4	0.400	0.664		0.754 (0.210–2.704)	0.085
CC	23	0.040	0	0.000	0.516		–	–
Allele
G	900	0.792	16	0.800	0.933		0.953 (0.316–2.878)	0.048
C	236	0.208	4	0.200
Haplotype
MIFCATT5-173G	406.0	0.357	6.8	0.340	0.858	0.973	1.080 (0.425–2.745)	0.050
MIFCATT6-173G	494.6	0.435	8.9	0.445	0.932		0.962 (0.395–2.341)	0.051
MIFCATT7-173G	4.3	0.004	0.0	0.000	0.800		–	–
MIFCATT5-173C	48.0	0.042	1.2	0.060	0.666		0.691 (0.107–4.475)	0.121
MIFCATT6-173C	14.4	0.013	0.1	0.005	0.760		2.555 (0.005–1.304)	0.003
MIFCATT7-173C	168.7	0.149	3.0	0.150	0.988		0.988 (0.287–3.409)	0.051

Notes:

^aP-values were tested with the χ² test.

^bGlobal P-value was calculated by Fisher’s exact test or Cochran–Armitage test for trend, as appropriate.

Abbreviations: MIF, macrophage migration inhibitory factor; OR, odds ratio; CI, confidence interval.