Table S1.
Polymorphism | Male suicide (n=408) |
Male control (n=340) |
P-valuea | Global P-valueb | OR (95% CI) | Power | ||
---|---|---|---|---|---|---|---|---|
N | Frequency | N | Frequency | |||||
MIF-794CATT5–8 | ||||||||
Genotype | ||||||||
55 | 56 | 0.137 | 49 | 0.144 | 0.788 | 0.584 | 0.945 (0.625–1.429) | 0.059 |
56 | 159 | 0.390 | 119 | 0.350 | 0.263 | 1.186 (0.880–1.599) | 0.193 | |
57 | 53 | 0.130 | 44 | 0.129 | 0.984 | 1.004 (0.654–1.542) | 0.050 | |
66 | 77 | 0.189 | 77 | 0.226 | 0.204 | 0.795 (0.557–1.133) | 0.256 | |
67 | 53 | 0.130 | 38 | 0.112 | 0.450 | 1.187 (0.761–1.850) | 0.108 | |
77 | 10 | 0.025 | 13 | 0.038 | 0.279 | 0.632 (0.274–1.460) | 0.194 | |
Allele | ||||||||
CATT5 | 324 | 0.397 | 261 | 0.384 | 0.601 | 0.875 | 1.057 (0.858–1.303) | 0.080 |
CATT6 | 366 | 0.449 | 311 | 0.457 | 0.733 | 0.965 (0.787–1.184) | 0.061 | |
CATT7 | 126 | 0.154 | 108 | 0.159 | 0.815 | 0.967 (0.731–1.280) | 0.058 | |
MIF-173G/C | ||||||||
Genotype | ||||||||
GG | 252 | 0.618 | 218 | 0.641 | 0.507 | 0.753 | 0.904 (0.671–1.218) | 0.100 |
GC | 136 | 0.333 | 102 | 0.300 | 0.330 | 1.167 (0.856–1.591) | 0.154 | |
CC | 20 | 0.049 | 20 | 0.059 | 0.553 | 0.825 (0.436–1.560) | 0.097 | |
Allele | ||||||||
G | 640 | 0.784 | 538 | 0.791 | 0.747 | 0.960 (0.748–1.231) | 0.062 | |
C | 176 | 0.216 | 142 | 0.209 | ||||
Haplotype | ||||||||
MIFCATT5-173G | 283 | 0.347 | 234.1 | 0.344 | 0.920 | 0.769 | 1.011 (0.816–1.253) | 0.052 |
MIFCATT6-173G | 357.4 | 0.438 | 300.6 | 0.442 | 0.875 | 0.984 (0.801–1.207) | 0.053 | |
MIFCATT7-173G | 2.1 | 0.003 | 0.1 | 0.000 | 0.208 | 17.54 (0.031–9.989) | 0.000 | |
MIFCATT5-173C | 41 | 0.050 | 26.9 | 0.040 | 0.320 | 1.284 (0.781–2.112) | 0.132 | |
MIFCATT6-173C | 8.6 | 0.011 | 10.4 | 0.015 | 0.413 | 0.686 (0.276–1.702) | 0.111 | |
MIFCATT7-173C | 123.9 | 0.152 | 107.9 | 0.159 | 0.715 | 0.949 (0.717–1.257) | 0.067 |
Notes:
P-values were tested with the χ2 test.
Global P-value was calculated by Fisher’s exact test or Cochran–Armitage test for trend, as appropriate.
Abbreviations: MIF, macrophage migration inhibitory factor; OR, odds ratio; CI, confidence interval.