Table 5.
Type | Cytobands | Training set | Validation set |
---|---|---|---|
p-value | p-value | ||
Gain | 1q21.1 | 0.055 | 0.0012 |
1q22 | 0.012 | 0.033 | |
1q23.1 | 0.038 | 0.024 | |
1q24.1 | 0.123 | 0.064 | |
1q32.3 | 0.099 | 0.14 | |
1q42.11 | 0.012 | 0.017 | |
1q42.12 | 0.08 | 0.015 | |
1q42.13 | 0.023 | 0.0059 | |
1q42.3 | 0.12 | 0.03 | |
1q43 | 0.0063 | 0.012 | |
1q44 | 0.021 | 0.049 | |
3q28 | 0.044 | 0.016 | |
8q13.2 | 0.044 | 0.054 | |
8q21.13 | 0.14 | 0.037 | |
8q22.1 | 0.092 | 0.06 | |
8q22.2 | 0.097 | 0.065 | |
8q23.2 | 0.12 | 0.0096 | |
8q24.11 | 0.075 | 0.049 | |
8q24.21 | 0.05 | 0.039 | |
8q24.22 | 0.012 | 0.086 | |
10p15.3 | 0.1 | 0.004 | |
10p12.32 | 0.12 | 0.013 | |
17q25.1 | 0.06 | 0.1 | |
Loss | 4q35.1 | 0.021 | 0.015 |
5q12.2 | 0.15 | 0.04 | |
5q14.3 | 0.06 | 0.1 | |
8p21.2 | 0.046 | 0.027 | |
8p21.1 | 0.085 | 0.043 | |
Xp22.13 | 0.066 | 0.046 | |
Xp21.2 | 0.049 | 0.059 | |
Xq13.3 | 0.066 | 0.053 | |
Xq21.2 | 0.14 | 0.12 | |
Xq21.32 | 0.066 | 0.053 |
Chromosome aberrations in cytobands are classified into two major types: amplifications/gains and deletions/losses. The p-values were calculated using the binomial test with respect to the global distribution