Table 3.

Molecular subtyping studies of pancreatic cancer

First author	Subtyping method	Molecular subtypes	Clinical significance
Collisson EA	Transcriptional profiles	3 subtypes: classical, quasi-mesenchymal, exocrine-like	Classical subtype - GATA6 - erlotinib; QM subtype - KRAS - gemcitabine
Moffitt RA	Transcriptional profiles	4 subtypes: classical and basal-like tumor subtypes and normal and activated stromal subtypes	/
Waddell N	Structural variations	4 subtypes: stable, locally rearranged, scattered, unstable	Unstable subtype - BRCA pathway - platinum-based therapy
Bailey P	Transcriptional profiles	4 subtypes: squamous, pancreatic progenitor, immunogenic, aberrantly differentiated endocrine exocrine	/