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. 2017 Mar 28;17:90. doi: 10.1186/s12887-017-0824-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Renal cortex under a 400 × light microscope after H-E staining. Similar treatment as Fig. 2 induced significant swelling of the renal tubular epithelial cells and interstitial tissue edema, which was improved by melatonin treatment in H-Estained samples (a and b). However, there were few changes regarding the glomeruli in these groups. In addition, the swollen renal tubular epithelial cells were quantified in the total renal tubular epithelial cells in the indicated groups.↗ represents cytotoxic edema, and▲ represents vasogenic edema