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. 2017 Mar 28;17:90. doi: 10.1186/s12887-017-0824-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Cerebral glial cells and capillaries assessed via a transmission electron microscope. HIBD could result in a remarkable pathologic change at 24 h after injury, including clearly decreased organelles and their extraordinary swelling, fused or disappeared intercellular junctions and additional stenosis and contracture of the capillary lumens (e-h) compared with sham group (a-d). Melatonin treatment could reduce the severity of pathology after injury (i-l). Red solid arrows represent tight junctions, red hollow arrows represent capillary lumens, and ▲ represents cell vacuoles