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. 2017 Mar 28;17:90. doi: 10.1186/s12887-017-0824-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Colon epithelial cells assessed via atransmission electron microscope. HIBD could result in edematous changes in the matrix, cristae in the mitochondria, the sparse distributed swelled microvilli, the vague epithelial cell organelles, remarkable decreased junctions and the loosened interstitial tissue (e-h) compared with sham group (ad). Melatonin treatment could reduce the severity of pathology after injury (i-l). Red solid arrows represent tight junctions, red hollow arrows represent intestinal epithelium microvilli, and ▲ represents mitochondria