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. 2017 Mar 28;17:90. doi: 10.1186/s12887-017-0824-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Real time-qPCR for ZO-1 in the cerebral cortex (a), renal cortex (b) and colon (c). HIBD induced a significant decrease in the ZO-1 mRNA expression in the cerebral cortex, renal cortex and colon. Melatonin treatment could significantly increase the ZO-1 mRNA expression in the renal cortex and colon in comparison with the one without melatonin treatment in HIBD group. The data represent the mean ± SD