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. 2017 Mar 29;49:35. doi: 10.1186/s12711-017-0311-8

Fig. 2.

Fig. 2

Effect of the multidimensional scaling (MDS) dimensions on the genomic inflation factor and on Manhattan plots of SNP significance. a Genomic inflation factor remained relatively unchanged as the number of MDS dimensions increased beyond the first 35 dimensions. be GWAS significance from PLINK using the first 35 to 50 MDS dimensions, showing that the significance patterns were virtually unchanged, with the exception of those for chromosome 12, which displayed decreasing significance as the number of MDS dimensions increased. All p values in the figures are on the log(1/p) scale