Table 3.
Chr | Region (Mb) | Size (Mb) | Most significant SNP | Contribution | Gene region | |||
---|---|---|---|---|---|---|---|---|
Name | MAF | p value | % of | % of | ||||
1 | 29.63–30.18 | 0.55 | S1_29635241 | 0.499 | 2.68 (10−07) | 2.25 | 1.51 | TNFAIP3, OLIG3 |
7 | 102.91–103.80 | 0.89 | S7_102911357 | 0.438 | 2.49 (10−16) | 7.35 | 6.98 | PTGR2 (U), FAM161B, LIN52, VRTN (U, D), FCF1, AREL1 (16 genes) |
7 | 116.07–117.43 | 1.36 | S7_116899295 | 0.342 | 2.97 (10−08) | 3.07 | 2.13 | GALC, KCNK10, SPATA7, PTPN21, ZC3H14, EML5, TTC8 |
11 | 56.56–58.58* | 2.21 | S11_58558301 | 0.422 | 7.14 (10−7) | 1.64 | 2.27 | SPRY2, SNORA70 |
11 | 77.75–79.69 | 1.94 | S11_79009219 | 0.226 | 9.16 (10−10) | 5.07 | 5.23 | FGF14, BIVM (U, D), LOC102167592, LOC102167785 (U) |
12 | 4.53–6.26* | 1.73 | S12_5615207 | 0.335 | 3.16 (10−07) | 2.59 | 2.63 | MFSD11-KCTD2 (49 genes) |
12 | 50.54–51.74 | 1.20 | S12_51574540 | 0.138 | 1.06 (10−07) | 0.64 | 1.16 | OR3A2, ASPA, TRPV3, TRPV1, CTNS, TAX1BP3, EMC6, CAMKK1 |
Chr = chromosome; MAF = minor allele frequency. is the additive heritability. is the observed accuracy of prediction. U indicate the significant SNP is located upstream of the gene. D indicates the significant SNP is located downstream of the gene. Contribution was calculated for the six most significant SNPs in each region. * This region has three significant SNPs