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. 2017 Mar 29;49:35. doi: 10.1186/s12711-017-0311-8

Table 3.

Chromosome regions with significant SNP effects on teat number

Chr Region (Mb) Size (Mb) Most significant SNP Contribution Gene region
Name MAF p value % of hα2 % of R^0
1 29.63–30.18 0.55 S1_29635241 0.499 2.68 (10−07) 2.25 1.51 TNFAIP3, OLIG3
7 102.91–103.80 0.89 S7_102911357 0.438 2.49 (10−16) 7.35 6.98 PTGR2 (U), FAM161B, LIN52, VRTN (U, D), FCF1, AREL1 (16 genes)
7 116.07–117.43 1.36 S7_116899295 0.342 2.97 (10−08) 3.07 2.13 GALC, KCNK10, SPATA7, PTPN21, ZC3H14, EML5, TTC8
11 56.56–58.58* 2.21 S11_58558301 0.422 7.14 (10−7) 1.64 2.27 SPRY2, SNORA70
11 77.75–79.69 1.94 S11_79009219 0.226 9.16 (10−10) 5.07 5.23 FGF14, BIVM (U, D), LOC102167592, LOC102167785 (U)
12 4.53–6.26* 1.73 S12_5615207 0.335 3.16 (10−07) 2.59 2.63 MFSD11-KCTD2 (49 genes)
12 50.54–51.74 1.20 S12_51574540 0.138 1.06 (10−07) 0.64 1.16 OR3A2, ASPA, TRPV3, TRPV1, CTNS, TAX1BP3, EMC6, CAMKK1

Chr = chromosome; MAF = minor allele frequency. hα2 is the additive heritability. R^0 is the observed accuracy of prediction. U indicate the significant SNP is located upstream of the gene. D indicates the significant SNP is located downstream of the gene. Contribution was calculated for the six most significant SNPs in each region. * This region has three significant SNPs