Fig 2.

(A-C). Hepatic Dmt1 expression was upregulated while Hamp expression and serum ferritin were downregulated in H. pylori-infected mice on ID diet. Hepatic Dmt1 expression was upregulated and Hamp expression was downregulated in H. pylori-infected mice on ID diet. (A) H. pylori-infected mice had significantly increased expression of Dmt1 compared to all other treatment groups. (B) Expression of Hamp in hepatic tissue was significantly downregulated in H. pylori -infected mice on ID diet compared to all other study groups. (C) Concurrent H. pylori infection and dietary ID decreased serum ferritin levels in female mice. H. pylori-infected mice on ID diet had significantly lower serum ferritin levels than both uninfected mice on IR diet and H. pylori-infected mice on IR diet. All data shown as mean + SEM. (*) = p<0.05, (**) = p<0.01, (****) = p<0.000.