Table 1. Polymyxin B Minimal Inhibitory Concentration (MIC) of H. pylori G27, X47 and 26695 Wild-type Strains and LPS Mutants.

Strains	Role in LPS biosynthesis	Polymyxin B MIC (μg/mL)
G27 wild-type	Full-length LPS	4.8 ± 1.1
G27ΔHP1284	Putative Hep III transferase	0.9 ± 0.1
G27ΔwaaL	O-antigen ligase	1.3 ± 0.3
G27ΔHP0579	KDO hydrolase	0.13 ± 0.0
X47 wild-type	Full-length LPS	332.8 ± 70.1
X47ΔHP1284	Putative Hep III transferase	106.7 ± 16.5
X47ΔwaaL	O-antigen ligase	58.7 ± 9.2
X47ΔHP0579-HP0580	KDO hydrolase	0.23 ± 0.03
26695 wild-type	Full-length LPS	149.3 ± 37.0
26695 HP1284::RC	Putative Hep III transferase	58.7 ± 9.2

MIC are reported as μg/mL and are the average of three experiments using polymyxin B Etest strips (Biomerieux) on CBA plates.