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. 2016 Apr 27;59(10):4625–4636. doi: 10.1021/acs.jmedchem.5b02001

Figure 4.

Figure 4

Co-crystal structure of sangivamycin 10 bound to HSP72. PDB 5AQZ, key hydrogen bonding interactions and their distances in Å are indicated. The key salt-bridge interaction between lysine-56 and glutamic acid-268 is absent. Only selected residues are shown and solvent has been omitted for clarity.