Table 1.
Demographic and biochemical parameter values in the subgroups of AMD patients and control group subjects
| Parameters | AMD Early (n = 31) | AMD Exudative (n = 75) | CG (n = 84) | p |
|---|---|---|---|---|
| Age (years) | 74.15 ± 6.3* | 70.49 ± 7.1* | 70.47 ± 4.18 | 0.019 |
| Gender (M/F) | 35.5/64.5 | 22.7/77.3 | 48/52 | 0.027 |
| Smokers (%) | 37.3 | 46.9 | 41.4 | 0.675 |
| SOD (IU/gHb)‡ | 1,169 ± 173* | 1,081.6 ± 170.3♦ | 1,079.3 ± 128.3 | 0.06 |
| GPx (IU/gHb)‡ | 40.1 ± 10.8* | 34.5 ± 10.0 | 39.9 ± 9.66 | 0.025 |
| GR (U/L)† | 51 (46–59) | 63 (46–72)♦ | 59 (54–64.5) | 0.07 |
| Albumin (g/L)‡ | 43.6 ± 2.6* | 42.8 ± 2.19*♦ | 44.8 ± 2.8 | 0.001 |
| Uric acid (µmol/L)† | 270 (211.8–288.5)* | 272 (219.5–316.5)* | 295.5 (248–350) | 0.006 |
| Bilirubine (µmol/L)† | 9.7 (7.8–13.2) | 11.2 (8.2–13.7) | 11.5 (9.0–14.3) | 0.430 |
| TAS (mmol/L)‡ | 1.18 ± 0.14* | 1.02 ± 0.22* | 1.31 ± 0.17 | <0.000 |
| CRP (mg/L)† | 2.4 (1.63–7.75) ♦ | 3.65 (2.10–6.10)* | 3.0 (1.65–4.10) | 0.05 |
| IL-6 (pg/ml)† | 2.82 (1.68–3.88) | 3.54 (1.57–15.89)* | 2.30 (1.52–3.48) | 0.07 |
| Fibrinogen (g/L)† | 3.91 (3.3–4.0) | 3.98 (3.3–4.6)* | 3.5 (3.0–4.0) | 0.007 |
AMD, The patients with Age-related Macular Degeneration; CG, the control group. ‡Values are presented as Arhitmethic mean ± SD. †Values are presented as Median and interquartile range. *p<0.05, difference between the tested group and the control group. ⧫p<0.05, difference between the early and late-exudative AMD group. P, significance of difference.