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. 2017 Mar 21;5(6):e13159. doi: 10.14814/phy2.13159

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© 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Number and diameter fractions per order. (A) Number fractions F _n(m) as function of order. (B) Diameter fractions of the vessels F _d(m) per order. The regression lines with their 95% confidence intervals are shown. The slope of F _n(m) is not significant (P = 0.70); the slope of F _d(m) is significant (P < 0.0001). The circles on the upper and lower confidence limits indicate the values of F _n(m) and F _d(m) that predict the worst case that a maximal number of vessels are involved with a minimal inner diameter, thereby contributing maximally to the resistance increase.