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. 2017 Mar 21;5(6):e13199. doi: 10.14814/phy2.13199

Figure 5.

Figure 5

Effect of butyrate stimulation on duodenal and colonic EC cells. (A) Time course of Ca2+ (i) changes in duodenal EC cells in response to butyrate, shown as % change from baseline. Dotted lines indicate SEM. Arrow indicates time of stimulus addition (= 4–5 mice). (B) AUC of Ca2+ (i) in duodenal EC cells. ***P < 0.001 (= 4–5 mice). (C) Release of 5‐HT from duodenal EC cells in culture following 2 h exposure to butyrate (But) or α‐MG (= 5 mice). (D) Time course of Ca2+ (i) changes in colonic EC cells in response to butyrate, shown as % change from baseline. Arrow indicates time of stimulus addition (= 3–4 mice). (E) AUC of Ca2+ (i) in colonic EC cells. **P < 0.01 (= 3–4 mice). (F) Release of 5‐HT from colonic EC cells in culture following 2 h exposure to butyrate. (= 5–7 mice). Data are shown as mean ± SEM. AUC, area under the curve