Table 5.
Comparison of reported laccase yields and volumetric activity in different expression hosts
| Source | Expression host | Laccase | Yield (mg l−1) | Vol. activity (U l−1) | Reference |
|---|---|---|---|---|---|
| Heterologous expression in yeast | |||||
| Trametes versicolor | Pichia pastoris | 2.8 | Bohlin et al. (2006) | ||
| Cryphonectria parasitica | Saccharomyces cerevisiae | lac3 | 41.5 | Kim et al. (2010) | |
| Pleurotus eryngii | Saccharomyces cerevisiae | 146 | Bleve et al. (2008) | ||
| Melanocarpus albomyces | Saccharomyces cerevisiae | 3 | 168 | Kiiskinen and Saloheimo (2004) | |
| Bacillus licheniformis | Pichia pastoris | 227.9 | Lu et al. (2013) | ||
| Moniliophthora perniciosa FA553 | Pichia pastoris | LacMP | 232 | Liu et al. (2015b) | |
| Melanocarpus albomyces | Saccharomyces cerevisiae | MaL | 7 | 270 | Andberg et al. (2009) |
| Ganoderma lucidum | Pichia pastoris | 580 | 685.8 | You et al. (2014) | |
| Pycnoporus cinnabarinus | Yarrowia lipolytica | 19.84 | 1024 | Madzak et al. (2005) | |
| Yarrowia lipolytica | Pichia pastoris | YlLac | 1290 | Kalyani et al. (2015) | |
| Bacillus subtilis | Pichia pastoris | CotA | 1648.15 | Wang et al. (2015) | |
| Ganoderma weberianum TZC-1 | Pichia pastoris GS115 | GwLac1 | 2260 | Zhou et al. (2014) | |
| Trametes trogii | Pichia pastoris | Lcc1 | 17 | 2520 | Colao et al. (2006) |
| Botrytis aclada | Pichia pastoris | 517 | 3220 | Kittl et al. (2012a) | |
| Ganoderma fornicatum 814 | Pichia pastoris | rLac1 | 3460 | Huang et al. (2011) | |
| Lenzites gibbosa | Pichia pastoris | 5406 | Zheng et al. (2014) | ||
| Trametes sp. AH 28-2 | Pichia pastoris | lacA | 4 | 5470 | Hong et al. (2006) |
| Rigidoporus microsporus (Fomes lignosus) | Pichia pastoris | 9.03 | 5950 | Liu et al. (2003) | |
| Thermus thermophilus SG0.5JP17-16 | Pichia pastoris | LacTT | 1200 | 6130 | Liu et al. (2015a) |
| Cerrena sp. HYB07 | Pichia pastoris | Lac1 | 19.3 | 6300 | Yang et al. (2015) |
| Pleurotus sajor-caju | Pichia pastoris | lac4 | 110 | 10,200 | Soden et al. (2002) |
| Trametes versicolor | Pichia methanolica | 12,600 | Guo et al. (2006) | ||
| Trametes versicolor | Pichia pastoris | lccA | 18,123 | Li et al. (2014) | |
| Botrytis aclada | Pichia pastoris | 495 | 51,000 | Kittl et al. (2012b) | |
| Trametes versicolor | Pichia pastoris | 140,000 | Hong et al. (2002) | ||
| Trametes sp. 420 | Pichia pastoris | 136 | 239,000 | Zhou et al. (2007) | |
| Pycnoporus cinnabarinus | Pichia pastoris | 8 | Otterbein et al. (2000) | ||
| Myceliophthora thermophila | Saccharomyces cerevisiae | 18 | Bulter et al. (2003) | ||
| Heterologous expression in filamentous fungi | |||||
| Trametes versicolor | Aspergillus niger | 2700 | Bohlin et al. (2006) | ||
| Pycnoporus coccineus | Aspergillus oryzae | 3000 | Hoshida et al. (2005) | ||
| Trametes hirsute | Penicillium canescens | 3000 | Abianova et al. (2010) | ||
| Myceliophthora thermophila | Aspergillus oryzae | r-MtL | 19 | Berka et al. (1997) | |
| Phlebia radiate | Trichoderma reesei | 20 | Saloheimo and Nikupaavola (1991) | ||
| Pycnoporus cinnabarinus | Aspergillus niger | 70 | Record et al. (2002) | ||
| Melanocarpus albomyces | Trichoderma reesei | 920 | Kiiskinen et al. (2004) | ||
| Trametes versicolor | Trichoderma reesei | 800–1000 | Baker and White (2001) | ||
| Heterologous expression in bacteria | |||||
| Bacillus pumilus W3 | Bacillus subtilis WB600 | CotA | 373,100 | Guan et al. (2015) | |
| Natural production host | |||||
| Trametes versicolor 1017 | Trametes versicolor 1017 | Tvlac | 10,000 | Chen et al. (2016b) | |
| Trametes sp. AH 28-2 | Trametes sp. AH 28-2 | rLacB | 31.6 | 32,000 | Li et al. (2007) |
| Trametes pubescens MB 89 | Trametes pubescens MB 89 | 65,000 | Galhaup and Haltrich (2001) | ||
| Trametes multicolor MB 49 | Trametes multicolor MB 49 | 85,000 | Hess et al. (2002) | ||
| Cerrena sp. WR1 | Cerrena sp. WR1 | Lcc3 | 200 | 202,000 | Chen et al. (2012) |
| Cerrena sp. HYB07 | Cerrena sp. HYB07 | LacA | 108 | 210,800 | Yang et al. (2014) |
| White rot fungus WR-1 | White rot fungus WR-1 | 692,000 | Revankar and Lele (2006) | ||