Table 4.
Summary of neuropsychological assessment
Domain/test | I Chemotherapy group (n = 22) |
II Chemo- and radiotherapy group (n = 11) |
III ALL control group (n = 12) |
I vs III (Mann-Whitney U test) |
II vs III (Mann-Whitney U test) |
I vs II (Mann-Whitney U test) |
Group interaction (Kruskal-Wallis test) |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Median | IQR | Median | IQR | Median | IQR | Z | p | Z | p | Z | p | Chi | p | |
IQ assessment | ||||||||||||||
WISC-R | 114.0 | 25.0 | 102.0 | 14.0 | 120 | 34.0 | 0.298 | 0.916 | 0.688 | 0.497 | 2.641 | <0.001 | 0.987 | 0.844 |
Memory and attention | ||||||||||||||
VCI | 44.0 | 9.0 | 46.0 | 18.0 | 59.0 | 25.0 | 1.446 | 0.159 | 2.101 | 0.047 | 1.069 | 0.285 | 2.256 | 0.498 |
RAVLT learning | 7.0 | 3.0 | 6.0 | 3.0 | 8.0 | 1.0 | 1.829 | 0.156 | 1.287 | 0.189 | 0.592 | 0.554 | 5.485 | 0.116 |
RAVLT interference | 11.0 | 3.0 | 8.0 | 2.4 | 9.0 | 1.0 | 2.059 | 0.004 | 0.534 | 0.597 | 3.418 | <0.001 | 17.589 | <0.001 |
RAVLT recall | 11.0 | 2.0 | 7.0 | 3.0 | 10.0 | 2.0 | 0.894 | 0.377 | 2.459 | 0.026 | 3.437 | <0.001 | 7.598 | 0.017 |
BVRT | 7.5 | 3.0 | 6.0 | 2.0 | 8.5 | 1.0 | 1.889 | 0.072 | 2.947 | 0.005 | 1.852 | 0.064 | 6.856 | 0.122 |
VFT phonemic | 8.7 | 1.7 | 7.7 | 4.7 | 10.9 | 3.0 | 2.894 | 0.013 | 2.259 | 0.031 | 1.375 | 0.169 | 5.688 | 0.095 |
VFT semantic | 17.5 | 4.0 | 15.0 | 4.0 | 24.0 | 5.0 | 2.987 | <0.001 | 2.984 | <0.001 | 3.684 | <0.001 | 17.459 | <0.001 |
Processing speed | ||||||||||||||
PSI | 24.0 | 5.0 | 21.0 | 4.0 | 24.0 | 2.0 | 0.784 | 0.624 | 1.008 | 0.584 | 2.444 | 0.015 | 3.468 | 0.415 |
Stroop test | 2.9 | 0.4 | 3.2 | 1.0 | 2.5 | 0.3 | 2.718 | <0.001 | 0.064 | 0.083 | 1.071 | 0.284 | 7.895 | 0.018 |
Executive functions | ||||||||||||||
CDT | 3.0 | 1.0 | 2.0 | 1.0 | 3.0 | 0 | 1.110 | 0.267 | 1.671 | 0.094 | 0.897 | 0.369 | 0.001 | 1.000 |
WCST achieved cat. | 4.5 | 1.0 | 3.0 | 2.0 | 5.0 | 1.5 | 1.658 | 0.099 | 2.947 | 0.011 | 2.081 | 0.037 | 13.259 | 0.004 |
WSCT trials to first cat. | 16.0 | 11.0 | 19.0 | 12.0 | 12.0 | 4.0 | 1.386 | 0.201 | 1.724 | 0.136 | 0.573 | 0.567 | 4.658 | 0.198 |
WSCT percentage of correct answers | 56.6 | 19.6 | 38.0 | 21.0 | 66.3 | 17.5 | 1.784 | 0.074 | 2.891 | 0.012 | 1.375 | 0.169 | 6.314 | 0.126 |
All data given in the table is scaled scores (adjusted for the children’s age)
Values in italics has statistical significance set at p < 0.05