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. 2017 Mar 30;8:195. doi: 10.3389/fphys.2017.00195

Figure 3.

Figure 3

Epicardial membrane potentials (Em) with different pH recovery protocols after acidosis. (A) The fast pH recovery of 0.1 min triggered suprathreshold delayed afterdepolarizations (DADs). (B) The slow pH recovery of 0.5 min triggered subthreshold DADs. (C) The gradual pH recovery of 4 min suppressed the occurrence of DADs. (D) pH recovery time for different simulation protocols. Each bar represents the time of pH recovery for each protocol. (E) The maximal amplitude of DADs after acidosis gradually decreased with the recovery time of pH. (F) The number of ectopic beats measured under each condition. Suprathreshold DADs (marked by an asterisk) were triggered in P_0 and P_0.1.