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. 2017 Mar 30;8:516. doi: 10.3389/fmicb.2017.00516

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Copyright © 2017 Mendoza-Martínez, Lara-Rojas, Sánchez and Aguirre.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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NapA is required for gene regulation in asexual spores. Transcriptomic analysis reveals that NapA is needed for the negative regulation of at least 13 genes (A) and the positive regulation of at least 201 genes (B) in conidia. (C) Confirmation of NapA-dependent expression of ethanol utilization genes during conidiation by qPCR. Genes alcA, aldA and alcR were used to confirm transcriptome results from conidia. Gene expression was normalized to H2B histone transcript levels. Data are mean values of three independent biological replicates. Bars represent the standard deviation (SD).