Table 2.
Down regulated transcripts in ΔnapA conidia.
| Gene | LogFC | Description | Domains |
|---|---|---|---|
| DNA BINDING | |||
| AN8426 | 3.3 | Conserved hypothetical protein | Fungal Zn(2)-Cys(6) binuclear cluster domain, Fungal specific transcription factor domain |
| AN3769 | 3.0 | C6 transcription factor | Fungal specific transcription factor domain |
| AN7118 | 2.9 | Putative transcription factor | Fungal specific transcription factor domain, Fungal Zn(2)-Cys(6) binuclear cluster domain, Zinc finger, C2H2 type |
| AN8103 | 2.8 | Putative transcription factor | Zn(II)2Cys6 transcription factor |
| AN4720 | 2.5 | conserved hypothetical protein | Zinc finger, C2H2 type |
| AN10897 | 2.4 | C6 zinc finger domain-containing protein | Fungal Zn(2)-Cys(6) binuclear cluster domain |
| AN7061 | 2.3 | Conserved hypothetical protein | Fungal specific transcription factor domain, Fungal Zn(2)-Cys(6) binuclear cluster domain |
| AN11831 | 2.3 | Conserved hypothetical protein | Fungal Zn(2)-Cys(6) binuclear cluster domain, Fungal specific transcription factor domain |
| AN4626 | 2.3 | Putative Zn(II)2Cys6 transcription factor | Has domain(s) with predicted RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity, role in regulation of transcription, DNA-templated and nucleus localization |
| AN8666 | 2.2 | C6 finger domain-containing protein | Fungal Zn(2)-Cys(6) binuclear cluster domain |
| AN7346 | 2.0 | Conserved hypothetical protein | Fungal Zn(2)-Cys(6) binuclear cluster domain, Fungal specific transcription factor domain |
| AN2667 | 2.0 | C6 transcription factor | Fungal specific transcription factor domain |
| OXIDOREDUCTASES | |||
| AN7418 | 5.5 | FAD monooxygenase | With predicted FAD binding, oxidoreductase activity and role in metabolic process |
| AN7981 | 3.8 | Ferric-chelate reductase | FAD-binding domain |
| AN10388 | 3.6 | Conserved hypothetical protein | Berberine and berberine like, FAD binding domain |
| AN11191 | 3.6 | Polyketide synthase | Beta-ketoacyl synthase, N-terminal domain, Beta-ketoacyl synthase, C-terminal domain, Acyl transferase domain, short chain dehydrogenase, KR domain |
| AN6096 | 3.4 | Conserved hypothetical protein | Aldo/keto reductase family |
| AN8349 | 3.3 | Salicylate hydroxylase | Pyridine nucleotide-disulphide oxidoreductase, FAD binding domain |
| AN0330 | 3.2 | NADH-dependent flavin oxidoreductase | NADH:flavin oxidoreductase / NADH oxidase family |
| AN10099 | 3.2 | Pyridoxamine phosphate oxidase | Pyridoxamine 5′-phosphate oxidase |
| AN2504 | 3.1 | Conserved hypothetical protein | FAD dependent oxidoreductase |
| AN0618 | 3.1 | Oxidoreductase | KR domain, short chain dehydrogenase |
| AN10005 | 3.0 | Short-chain dehydrogenase/reductase SDR | Short chain dehydrogenase |
| AN8979 | 2.8 | AlcA, Alcohol dehydrogenase I | Alcohol dehydrogenase GroES-like domain, Zinc-binding dehydrogenase |
| AN4643 | 2.8 | Conserved hypothetical protein | Cytochrome P450 |
| AN2704 | 2.8 | Conserved hypothetical protein | GMC oxidoreductase |
| AN10296 | 2.8 | FAD dependent oxidoreductase | FAD binding domain, flavo_cyto_c: flavocytochrome c, FAD dependent oxidoreductase, Flavin containing amine oxidoreductase |
| AN6414 | 2.8 | Conserved hypothetical protein | Cytochrome P450 |
| AN2682 | 2.8 | 12-oxophytodienoate reductase | NADH:flavin oxidoreductase / NADH oxidase family |
| AN1548 | 2.7 | Short-chain dehydrogenase | Not found |
| AN10667 | 2.7 | Alcohol dehydrogenase | Alcohol dehydrogenase GroES-like domain, Zinc-binding dehydrogenase |
| AN2723 | 2.7 | Histidinol dehydrogenase | Histidinol dehydrogenase, hisD: histidinol dehydrogenase |
| AN7388 | 2.6 | Catalase-peroxidase | Peroxidase, cat_per_HPI: catalase/peroxidase HPI |
| AN5287 | 2.6 | Acyl-CoA dehydrogenase family member 11 | Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, C-terminal domain |
| AN5421 | 2.5 | Steroid monooxygenase | Not found |
| AN3400 | 2.5 | Short chain type dehydrogenase | KR domain, short chain dehydrogenase |
| AN3206 | 2.5 | Glucose-methanol-choline oxidoreductase | GMC oxidoreductase |
| AN7415 | 2.5 | Conserved hypothetical protein | FAD binding domain |
| AN1034 | 2.5 | Polyketide synthase | NAD dependent epimerase/dehydratase, short chain dehydrogenase, Methyltransferase domain, Male sterility protein, Acyl transferase domain, Phosphopantetheine attachment site, Beta-ketoacyl synthase, C-terminal domain, Beta-ketoacyl synthase, N-terminal domain |
| AN0027 | 2.5 | Cyclohexanone monooxygenase | Flavin-binding monooxygenase-like, Pyridine nucleotide-disulphide oxidoreductase |
| AN0554 | 2.4 | Aldehyde dehydrogenase ALDH | Aldehyde dehydrogenase family |
| AN5854 | 2.4 | Oxidoreductase | 2-nitropropane dioxygenase, FMN-dependent dehydrogenase, Conserved region in glutamate synthase |
| AN8547 | 2.3 | GMC oxidoreductase | GMC oxidoreductase |
| AN2389 | 2.3 | Ketopantoate reductase | Ketopantoate reductase PanE/ApbA C terminal, apbA_panE: 2-dehydropantoate 2-reductase, Ketopantoate reductase PanE/ApbA |
| AN1825 | 2.3 | Sulfide:quinone oxidoreductase | Pyridine nucleotide-disulphide oxidoreductase |
| AN11096 | 2.3 | Conserved hypothetical protein | Short chain dehydrogenase |
| AN5360 | 2.3 | Conserved hypothetical protein | Cytochrome P450 |
| AN5373 | 2.3 | 3-oxoacyl-(acyl-carrier-protein) reductase | Short chain dehydrogenase, 23BDH: acetoin reductases |
| AN8250 | 2.3 | Conserved hypothetical protein | Cytochrome P450 |
| AN4126 | 2.3 | Aldehyde dehydrogenase | Aldehyde dehydrogenase family |
| AN2396 | 2.3 | Conserved hypothetical protein | NAD dependent epimerase/dehydratase family |
| AN2666 | 2.2 | Sorbitol/xylitol dehydrogenase | Zinc-binding dehydrogenase, bchC: Chlorophyll synthesis pathway, bchC, Alcohol dehydrogenase GroES-like domain |
| AN9315 | 2.2 | Conserved hypothetical protein | Pyridine nucleotide-disulphide oxidoreductase |
| AN2335 | 2.2 | 3-hydroxyisobutyrate dehydrogenase | NAD binding domain of 6-phosphogluconate |
| AN4829 | 2.1 | Alcohol dehydrogenase | Aldo/keto reductase family |
| AN3399 | 2.0 | FAD binding oxidoreductase | FAD binding domain |
| AN5550 | 2.0 | Conserved hypothetical protein | FAD binding domain |
| AN6659 | 2.0 | Short chain dehydrogenase | KR domain, short chain dehydrogenase, NAD dependent epimerase/dehydratase |
| TRANSPORTER ACTIVITY | |||
| AN9000 | 4.4 | MFS transporter | Major Facilitator Superfamily |
| AN10891 | 3.8 | High-affinity glucose transporter | SP: MFS transporter, sugar porter (SP) family, Sugar (and other), Major Facilitator Superfamily |
| AN8981 | 3.6 | AlcS, conserved hypothetical protein | GPR1/FUN34/yaaH family |
| AN6019 | 3.5 | MFS transporter | Major Facilitator Superfamily |
| AN12129 | 3.0 | Conserved hypothetical protein | Major Facilitator Superfamily, Sugar (and other) transporter |
| AN2368 | 3.0 | Membrane transporter | Major Facilitator Superfamily |
| AN9010 | 2.8 | MFS nicotinic acid transporter Tna1 | Major Facilitator Superfamily |
| AN2699 | 2.8 | Conserved hypothetical protein | Major Facilitator Superfamily, Ion channel regulatory protein UNC-93 |
| AN7380 | 2.7 | Conserved hypothetical protein | Major Facilitator Superfamily |
| AN11211 | 2.6 | Uracil permease | Permease for cytosine/purines, uracil, thiamine, allantoin, ncs1: NCS1 nucleoside transporter family |
| AN5275 | 2.6 | Choline transporter | Amino acid permease |
| AN2665 | 2.5 | MFS sugar transporter | Major Facilitator Superfamily, Major Facilitator Superfamily, Sugar (and other) |
| AN2358 | 2.5 | Conserved hypothetical protein | Sugar (and other), Major Facilitator Superfamily |
| AN8995 | 2.5 | Conserved hypothetical protein | Major Facilitator Superfamily |
| AN3207 | 2.5 | Amino acid transporter | Transmembrane amino acid transporter protein |
| AN9165 | 2.4 | Conserved hypothetical protein | Sugar (and other) transporter, Major Facilitator Superfamily |
| AN3352 | 2.4 | Conserved hypothetical protein | ncs1: NCS1 nucleoside transporter family, Permease for cytosine/purines, uracil, thiamine, allantoin |
| AN2201 | 2.4 | Proline permease | Amino acid permease |
| AN8352 | 2.4 | Carbixilic Transporter | Not found |
| AN8941 | 2.4 | Na/K ATPase alpha 1 isoform | Cation transporting ATPase, C-terminus, haloacid dehalogenase-like hydrolase, ATPase_P-type: HAD ATPase, P-type, family IC, E1-E2 ATPase |
| AN2959 | 2.3 | Allantoate transporter | Major Facilitator Superfamily |
| AN6063 | 2.2 | MFS transporter | Major Facilitator Superfamily, 2_A_01_02: Multidrug resistance protein, Sugar (and other) transporter, pump (TRI12) |
| AN12222 | 2.2 | Conserved hypothetical protein | Major Facilitator Superfamily |
| AN8955 | 2.2 | Conserved hypothetical protein | Major Facilitator Superfamily |
| AN3503 | 2.2 | Allantoate permease | Major Facilitator Superfamily |
| AN5187 | 2.1 | Na(+)/H(+) antiporter | Sodium/hydrogen exchanger family |
| AN2814 | 2.1 | MFS lactose permease | Major Facilitator Superfamily, SP: MFS transporter, sugar porter (SP) family |
| AN6960 | 2.1 | Conserved hypothetical protein | WD domain, G-beta repeat, Ankyrin repeat, CorA-like Mg2+ transporter |
| AN6451 | 2.1 | Conserved hypothetical protein | Major Facilitator Superfamily, Sugar (and other) transporter, 2_A_01_02: Multidrug resistance protein, Fungal trichothecene efflux pump (TRI12) |
| AN7067 | 2.0 | Conserved hypothetical protein | Major Facilitator Superfamily, SP: MFS transporter, sugar porter (SP) family, Sugar (and other) |
| AN10305 | 2.0 | Vacuolar membrane ATPase C | V_ATP_synt_C: V-type ATPase, C subunit, ATP synthase subunit C |
| AN9336 | 2.0 | Conserved hypothetical protein | Major Facilitator Superfamily |
| HYDROLASES | |||
| AN2690 | 4.0 | Conserved hypothetical protein | Glycosyl hydrolases family 16 |
| AN10346 | 3.8 | Cutinase | Cutinase, Phospholipase/Carboxylesterase |
| AN3402 | 3.8 | Alpha-amylase | Starch binding domain, Domain of unknown function (DUF1966), Alpha amylase, catalytic domain |
| AN8899 | 3.8 | 1-aminocyclopropane-1-carboxylate deaminase | Pyridoxal-phosphate dependent enzyme, ACC_deam: 1-aminocyclopropane-1- |
| AN5422 | 3.8 | Beta-lactamase | Beta-lactamase |
| AN6097 | 3.7 | Conserved hypothetical protein | 3-carboxy-cis,cis-muconate lactonizing enzyme |
| AN2834 | 3.5 | Conserved hypothetical protein | GDSL-like Lipase/Acylhydrolase |
| AN1792 | 3.5 | GDSL Lipase/Acylhydrolase | GDSL-like Lipase/Acylhydrolase |
| AN2539 | 3.3 | Haloalkanoic acid dehalogenase | HAD_type_II: haloacid dehalogenase, type II, HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 |
| AN3777 | 3.1 | Endo-beta-1,6-glucanase | Cellulase (glycosyl hydrolase family 5) |
| AN0022 | 3.1 | Alpha-galactosidase/alpha-n-acetylgalactosaminidase | Melibiase |
| AN11051 | 3.0 | Extracellular chitosanase CsnC | Fungal chitosanase |
| AN3613 | 2.8 | Xylanase | Glycosyl hydrolases family 11 |
| AN5060 | 2.7 | Conserved hypothetical protein | Has domain(s) with predicted arylformamidase activity and role in tryptophan catabolic process to kynurenine |
| AN11219 | 2.7 | Glutamyl-tRNA(Gln) amidotransferase subunit A | Amidase |
| AN10333 | 2.7 | Metallopeptidase, putative | Has domain(s) with predicted hydrolase activity and role in metabolic process |
| AN6656 | 2.6 | Endo-polygalacturonase D | Glycosyl hydrolases family 28 |
| AN9518 | 2.5 | Haloalkanoic acid dehalogenase | HAD_type_II: haloacid dehalogenase, type II, HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 |
| AN7275 | 2.5 | Xylosidase/glycosyl hydrolase | Glycosyl hydrolases family 43 |
| AN0181 | 2.4 | Conserved hypothetical protein | Thioesterase superfamily |
| AN8977 | 2.4 | AlcP, Conserved hypothetical protein | Strictosidine synthase, SMP-30/Gluconolactonase/LRE-like region |
| AN5608 | 2.4 | Conserved hypothetical protein | Carboxylesterase |
| AN1043 | 2.3 | Conserved hypothetical protein | Glycosyl hydrolases family 43 |
| AN2779 | 2.2 | Dipeptidase | Amidohydrolase family |
| AN2388 | 2.2 | Beta-1,4-endoglucanase | Not found |
| AN1826 | 2.1 | Metallo-beta-lactamase domain-containing protein | Metallo-beta-lactamase superfamily |
| AN2424 | 2.1 | Beta-N-acetylhexosaminidase | Glycosyl hydrolase family 20, catalytic domain |
| AN7911 | 2.1 | Conserved hypothetical protein | Amidohydrolase |
| AN2777 | 2.0 | Fumarylacetoacetate hydrolase | Fumarylacetoacetate (FAA) hydrolase family, alpha/beta hydrolase fold |
| UNCLASSIFIED | |||
| AN2587 | 8.7 | Conserved hypothetical protein | CFEM domain |
| AN11810 | 3.7 | Putative GNAT-type acetyltransferase | Not found |
| AN8980 | 3.4 | AlcM, conserved hypothetical protein | Not found |
| AN8092 | 3.3 | Conserved hypothetical protein | pfs domain Potential Cdc28p substrate |
| AN0180 | 3.0 | Putative Enoyl-CoA hydratase | Enoyl-CoA hydratase/isomerase family |
| AN7539 | 3.0 | Hydrophobin | Fungal hydrophobin |
| AN8913 | 3.0 | Predicted glycosylphosphatidylinositol (GPI)-anchored protein | Not found |
| AN8614 | 2.7 | Conserved hypothetical protein | Cupin domain |
| AN9354 | 2.7 | Putative transcription factor | NmrA-like family Transcription factor |
| AN2954 | 2.6 | Extracellular serine-rich protein | Not found |
| AN1982 | 2.5 | Cell cycle regulatory protein, putative | WD domain |
| AN5273 | 2.5 | Hydroxymethylglutaryl-CoA lyase | Enoyl-CoA hydratase/isomerase family,HMGL-like |
| AN8468 | 2.2 | Wd-repeat protein | NACHT domain, WD domain |
| AN9297 | 2.2 | FAD binding, oleate hydratase activity and role in fatty acid metabolic process | Not found |
| AN8622 | 2.2 | Phosphodiesterase/alkaline phosphatase D | PhoD-like phosphatase |
| AN1046 | 2.2 | Chitin synthase D | Chitin synthase |
| AN2022 | 2.2 | Putative heterokaryon incompatibility protein | Not found |
| AN11080 | 2.1 | DMATS type aromatic prenyltransferase | Tryptophan dimethylallyltransferase, arom_pren_DMATS: aromatic prenyltransferase, DMATS type |
| AN3730 | 2.1 | 1,3-beta-glucanosyltransferase | X8 domain, Glycolipid anchored surface protein (GAS1) |
| AN0017 | 2.1 | Conserved hypothetical protein | CutC family |
| AN2623 | 2.1 | Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase | Not found |
| AN5833 | 2.1 | Acyl-CoA synthetase | AMP-binding enzyme, Domain of unknown function (DUF3448) |
| AN7279 | 2.1 | GPI anchored protein poly(beta-D-mannuronate) lyase activity | Not found |
| AN2346 | 2.1 | Conserved hypothetical protein | Pfs domain |
| AN10302 | 2.1 | Hypothetical protein | NACHT domain |
| AN3159 | 2.0 | Conserved hypothetical protein | RasGEF domain |
| AN8368 | 2.0 | Conserved hypothetical protein | Spherulation-specific family 4 |
| AN2778 | 2.0 | Conserved hypothetical protein | Cytochrome b5-like Heme/Steroid binding domain |
| HYPOTHETICAL PROTEINS WITH NO IDENTIFIED DOMAINS | |||
| AN2676 | 4.9 | Conserved hypothetical protein | Not found |
| AN7203 | 3.5 | Conserved hypothetical protein | Not found |
| AN8369 | 3.4 | Predicted protein | Not found |
| AN11341 | 3.2 | Predicted protein | Not found |
| AN10086 | 3.1 | DUF1446 domain-containing protein | Protein of unknown function (DUF1446) |
| AN9331 | 3.1 | Conserved hypothetical protein | Not found |
| AN6797 | 3.1 | Conserved hypothetical protein | Not found |
| AN4122 | 3.1 | Conserved hypothetical protein | Protein of unknown function |
| AN2322 | 3.0 | Conserved hypothetical protein | Not found |
| AN10360 | 2.9 | Conserved hypothetical protein | Not found |
| AN9323 | 2.9 | Conserved hypothetical protein | Not found |
| AN7261 | 2.8 | Conserved hypothetical protein | Not found |
| AN5190 | 2.8 | Conserved hypothetical protein | Not found |
| AN2700 | 2.8 | Conserved hypothetical protein | Not found |
| AN0972 | 2.7 | Conserved hypothetical protein | Not found |
| AN2750 | 2.7 | Conserved hypothetical protein | Not found |
| AN1928 | 2.7 | Conserved hypothetical protein | Not found |
| AN12341 | 2.7 | Hypothetical protein | Not found |
| AN1042 | 2.7 | Conserved hypothetical protein | Not found |
| AN10326 | 2.6 | Predicted protein | Not found |
| AN7333 | 2.6 | Conserved hypothetical protein | Not found |
| AN12061 | 2.6 | Conserved hypothetical protein | Not found |
| AN8240 | 2.6 | Conserved hypothetical protein | Not found |
| AN7985 | 2.5 | Conserved hypothetical protein | Not found |
| AN11290 | 2.5 | Conserved hypothetical protein | Not found |
| AN7270 | 2.5 | Conserved hypothetical protein | Not found |
| AN4554 | 2.5 | Conserved hypothetical protein | Not found |
| AN11809 | 2.5 | Conserved hypothetical protein | Not found |
| AN2041 | 2.4 | Conserved hypothetical protein | Not found |
| AN10048 | 2.4 | Conserved hypothetical protein | Not found |
| AN1925 | 2.4 | Conserved hypothetical protein | Not found |
| AN8994 | 2.4 | Conserved hypothetical protein | Not found |
| AN11281 | 2.4 | Conserved hypothetical protein | Not found |
| AN12238 | 2.3 | Conserved hypothetical protein | Not found |
| AN10320 | 2.3 | Conserved hypothetical protein | Not found |
| AN9521 | 2.2 | Conserved hypothetical protein | Not found |
| AN7124 | 2.2 | Conserved hypothetical protein | Not found |
| AN4319 | 2.2 | Conserved hypothetical protein | Not found |
| AN0005 | 2.2 | Hypothetical protein | Not found |
| AN4136 | 2.2 | Conserved hypothetical protein | Not found |
| AN11585 | 2.2 | Conserved hypothetical protein | Not found |
| AN7976 | 2.1 | Conserved hypothetical protein | Not found |
| AN11872 | 2.1 | Predicted protein | Not found |
| AN8148 | 2.1 | Conserved hypothetical protein | Not found |
| AN6648 | 2.1 | Conserved hypothetical protein | Not found |
| AN11777 | 2.1 | Predicted protein | Not found |
| AN11865 | 2.1 | Conserved hypothetical protein | Not found |
| AN0481 | 2.1 | Conserved hypothetical protein | Not found |
| AN8008 | 2.1 | Conserved hypothetical protein | Not found |
| AN1649 | 2.1 | Conserved hypothetical protein | Not found |
| AN7099 | 2.1 | Conserved hypothetical protein | Not found |
| AN8740 | 2.1 | Conserved hypothetical protein | Not found |
| AN4642 | 2.0 | Conserved hypothetical protein | Not found |
| AN0539 | 2.0 | Conserved hypothetical protein | Not found |