Table 1. Numbers of subtilase superfamily genes in different fungal species.
| Species | Proteinase K-like | Pyrolisin | Kexin | S53 | OSP | New 1 | New 2 | New 3 | New 4 | Total |
|---|---|---|---|---|---|---|---|---|---|---|
| Phaeosphaeria nodorum46 | 5 (2)* | 1 (1) | 1 | 5 | / | / | 1 | / | / | 13 (3) |
| Pyrenophora tritici-repentis47 | 5 | 3 | 1 | 4 (1) | / | / | / | / | / | 13 (1) |
| Aspergillus clavatus48 | 2 | / | 1 | 1 | 1 | / | / | / | / | 5 |
| Aspergillus flavus49 | 2 | / | 1 (1) | 2 | 1 | 1 | / | / | / | 7 (1) |
| Aspergillus fumigatus50 | 3 | / | 1 | 2 | / | / | / | 1 | / | 7 |
| Aspergillus fischeri50 | 3 | / | 1 | 2 | / | / | / | 2 | / | 8 |
| Aspergillus nidulans51 | 2 | / | 1 | 1 | / | / | / | / | / | 4 |
| Aspergillus niger52 | 2 | / | 1 | 3 | / | 3 | 1 | / | / | 10 |
| Aspergillus oryzae53 | 2 | / | 1 | 2 | / | / | / | / | / | 5 |
| Aspergillus terreus54 | 2 | 1 | 1 | 1 | / | 1 | / | / | / | 6 |
| Penicillium chrysogenum55 | 2 | / | 1 | 2 | / | / | / | / | / | 5 |
| Penicillium marneffei56 | 1 | / | 1 | 3 (1) | 1 | 1 | 1 | / | / | 8 (1) |
| Coccidioides immitis57 | 14 | / | 1 | 3 | / | / | / | / | / | 18 |
| Coccidioides posadasii57 | 14 | 0 (1) | 1 | 3 | 1 | / | / | / | / | 19 (1) |
| Microsporum canis58 | 12 | / | 1 | 4 | 1 | / | 2 (1) | / | / | 20 (1) |
| Paracoccidioides brasiliensis59 | 2 | / | 1 | 2 | 1 | / | / | 2 | / | 8 |
| Blastomyces dermatitidis60 | 2 | / | 1 | 2 | 1 | / | / | 1 | / | 7 |
| Histoplasma capsulatum61 | 2 | / | 1 | 2 | 1 | / | / | 1 | / | 7 |
| Microsporum gypseum62 | 11 (1) | / | 1 | 2 | 1 | / | / | / | / | 15 (1) |
| Uncinocarpus reesii57 | 15 | 0 (1) | 1 | 3 | 2 | / | / | / | / | 21 (1) |
| Trichophyton rubrum62 | 12 | / | 2 | 3 | 1 | / | 0 (1) | / | / | 18 (1) |
| Trichophyton tonsurans62 | 12 (1) | / | 3 | 3 | 1 | / | 0 (1) | / | / | 19 (2) |
| Trichophyton equinum62 | 12 | / | 2 | 3 | 1 | / | 0 (1) | / | / | 18 (1) |
| Chaetomium globosum63 | 4 (1) | 1 | 1 | 1 | / | 2 | 1 (2) | / | / | 10 (3) |
| Epichloë festucae1,64 | 8 | 4 | 2 | / | 1 | / | / | / | / | 15 |
| Fusarium graminearum65,66 | 11 | 3 | 1 | 1 | 1 | 3 (1) | 1 (1) | / | / | 21 (2) |
| Fusarium oxysporum67 | 12 (2) | 2 (2) | 1 | 1 | 1 | 1 (2) | 1 (2) | / | / | 19 (8) |
| Fusarium solani67 | 6 | 8 | 1 | 1 (1) | / | 4 | 8 (1) | / | / | 28 (2) |
| Fusarium verticillioides65,67 | 11 (2) | 1 (2) | 1 | 2 (1) | 2 | 1 (1) | 1 | / | / | 19 (6) |
| Magnaporthe grisea68 | 6 (1) | 16 | 1 | 1 | / | / | 0 (1) | / | / | 24 (2) |
| Magnaporthe poae68 | 3 (1) | 9 (1) | 1 | / | / | 1 (1) | 16 (3) | / | / | 30 (6) |
| Metarhizium acridum69 | 15 (2) | 7 (1) | 1 | 2 | 1 | 0 (1) | 2 (1) | / | / | 28 (5) |
| Metarhizium anisopliae69 | 19 | 9 (3) | 1 | 5 | 2 | 2 (1) | 5 | / | / | 43 (4) |
| Metarhizium robertsii69 | 19 (1) | 11 (1) | 1 | 4 | 3 | 3 (1) | 7 | / | / | 48 (3) |
| Verticillium dahliae70 | 6 | 6 (4) | 1 | / | / | 1 | / | / | / | 14 (4) |
| Verticillium albo-atrum70 | 4 (2) | 10 (2) | 1 | / | / | 1 | / | / | / | 16 (4) |
| Neurospora crassa71 | 3 | 1 | 1 | 3 | / | 1 | / | / | / | 9 |
| Podospora anserina72 | 6 (2) | 1 | 1 | 2 | / | 2 | 1 | 1 | / | 14 (2) |
| Trichoderma reesei73 | 5 | 5 | 1 | 5 | / | 3 | 3 | / | / | 22 |
| Botryotinia fuckeliana74 | 1 (1) | 1 | 1 | 2 | / | / | / | / | / | 5 (1) |
| Sclerotinia sclerotiorum74 | 2 | 1 | 1 | 4 | / | / | / | / | / | 8 |
| Arthrobotrys oligospora75 | 19 (1) | 2 | 1 | 1 | 1 | 2 | 2 | / | / | 28 (1) |
| Pichia pastoris76,77 | 3 | 1 | 1 | / | / | / | / | / | / | 5 |
| Zygosaccharomyces rouxii78,79 | 3 | / | 1 | / | / | / | / | / | / | 4 |
| Lachancea thermotolerans80 | 3 | / | 1 | / | / | / | / | / | / | 4 |
| Ashbya gossypii81 | 2 | / | 1 | / | / | / | / | / | / | 3 |
| Candida albicans82 | 4 | / | 1 | / | / | / | / | / | / | 5 |
| Candida dubliniensis83 | 4 | / | 1 | / | / | / | / | / | / | 5 |
| Candida glabrata84 | 4 | / | 1 | / | / | / | / | / | / | 5 |
| Candida lusitaniae82 | 3 | / | 1 | / | / | / | / | / | / | 4 |
| Candida parapsilosis85 | 4 | / | 1 | / | / | / | / | / | / | 5 |
| Candida tropicalis82 | 4 | / | 1 | / | / | / | / | / | / | 5 |
| Candida guilliermondii82 | 3 | / | 1 | / | / | / | / | / | / | 4 |
| Debaryomyces hansenii84 | 3 | / | 1 | / | / | / | / | / | / | 4 |
| Kluyveromyces lactis84 | 2 | / | 1 | / | / | / | / | / | / | 3 |
| Lodderomyces elongisporus82 | 3 | / | 1 | / | / | / | / | / | / | 4 |
| Pichia stipitis86 | 3 | / | 1 | / | / | / | / | / | / | 4 |
| Saccharomyces cerevisiae87 | 3 | / | 1 | / | / | / | / | / | / | 4 |
| Saccharomyces kluyveri79,88 | 1 | / | / | / | / | / | / | / | / | 1 |
| Saccharomyces kudriavzevii88 | 2 | / | / | / | / | / | / | / | / | 2 |
| Saccharomyces mikatae88 | 3 (1) | / | / | / | / | / | / | / | / | 3 (1) |
| Saccharomyces castellii88 | 3 (3) | / | 1 | / | / | / | / | / | / | 4 (3) |
| Vanderwaltozyma polyspora89 | 5 | / | 1 | / | / | / | / | / | / | 6 |
| Yarrowia lipolytica90,91 | 16 | / | 1 | / | / | / | / | / | / | 17 |
| Schizosaccharomyces japonicus92 | 2 | / | 1 | / | / | / | / | / | 1 | 4 |
| Schizosaccharomyces pombe93 | 2 | / | 1 | / | / | / | / | / | 1 | 4 |
| Schizosaccharomyces cryophilus92 | 2 | / | 1 | / | / | / | / | / | 1 | 4 |
| Schizosaccharomyces octosporus66 | 2 | / | 1 | / | / | / | / | / | 1 | 4 |
| Cryptococcus neoformans94 | 1 | 1 | 1 | / | / | / | / | / | / | 3 |
| Laccaria bicolor95 | 2 | 1 | 2 | 3 | / | / | / | / | / | 8 |
| Phanerochaete chrysosporium96 | 1 | 2 | / | 4 (2) | / | / | / | / | / | 7 (2) |
| Postia placenta97 | 2 | / | 1 | 23 | / | / | / | / | / | 26 |
| Puccinia graminis98 | 3 | 8 (2) | 1 | 2 | / | / | / | / | / | 14 (2) |
| Malassezia globosa99 | 1 | / | 1 | / | / | / | / | / | 1 | 3 |
| Ustilago maydis100 | 1 | 1 | 1 | / | / | / | / | / | 1 | 4 |
| Coprinus cinereus101 | 6 | 2 | 2 (1) | 1 | / | / | / | / | / | 11 (1) |
| Sporobolomyces roseus | 2 | / | 1 | / | / | / | / | / | / | 3 |
| Rhizopus oryzae102 | 10 (1) | 8 (1) | 2 (1) | / | / | / | / | / | 1 | 21 (3) |
| Phycomyces blakesleeanus103 | 10 (1) | 9 (3) | 2 | / | / | / | / | / | 1 | 22 (4) |
| Batrachochytrium dendrobatidis104 | 1 (1) | / | 0 (2) | / | / | / | / | / | 1 (1) | 2 (4) |
| Encephalitozoon cuniculi105 | 1 | / | / | / | / | / | / | / | / | 1 |
| Enterocytozoon bieneusi106,107 | / | / | 0 (1) | / | / | / | / | / | / | 0 (1) |
| Encephalitozoon intestinalis108 | / | / | 0 (1) | / | / | / | / | / | / | 0 (1) |
*Numbers in brackets represent the deleted gene numbers which show ambiguously aligned regions around the three active catalytic residues.