Figure 7.

Biochemical analysis of serum and urine from Loxosceles venom and tetracycline treated group. BALB/c mice were injected with 9.6 µg of venom and, after 30 min, treated three times every 4 h with 200 µL of tetracycline [5 mg/mL]. Control animals were injected with Phosphate-buffered saline—PBS (B). Urine samples, collected from each animal during 24 h of the treatments, were analyzed for the presence of protein (A) and creatinine (B). Serum samples, collected 24 h after buffer/venom injection, were analyzed for the presence of urea (C) and albumin (D). Results are representative of two independent experiments and expressed as the mean of triplicates ± standard deviation. Significant differences (*) p < 0.05.