Table 2.
Clinical conditions exhibiting elevated SDMA levels.
| Patient Population | N | Correlation with Clinical Outcome | Year of First Report | Ref. |
|---|---|---|---|---|
| CKD/ESRD | 10 | SDMA correlates with renal function | 1996 | [44,95] |
| Childhood hypertension | 38 | SDMA correlates with GFR | 1997 | [48] |
| Hyperthyroidism | 19 | ND | 2002 | [56] |
| Critical illness in intensive care unit | 52 | SDMA correlates with creatinine level | 2003 | [57] |
| Hepatorenal syndrome | 11 | ND | 2006 | [63] |
| Coronary artery disease | 145 | SDMA negatively correlates with GFR | 2006 | [64] |
| Type 2 diabetes mellitus (DM) | 103 | Elevated SDMA in type 2 DM with albuminuria | 2007 | [96] |
| Alcoholic hepatitis | 52 | ND | 2007 | [97] |
| Heart failure | 132 | ND | 2008 | [98] |
| Preeclampsia | 47 | ND | 2009 | [99] |
| Stroke | 394 | SDMA predicts all-cause mortality | 2010 | [100] |
| Polycystic ovary syndrome (PCOS) | 16 | ND | 2011 | [101] |
| Glaucoma | 210 | Elevated SDMA in advanced glaucoma | 2012 | [80] |
| Hyperuricemia | 58 | SDMA correlates with uric acid level | 2013 | [102] |
| Malaria | 123 | ND | 2014 | [103] |
Studies tabulated according to year of first report. ND, not determined.