Table 2.
Mass spectrometry specificity studies.
| Organism/Toxin | Source | Peptide Substrate Type A | Peptide Substrate Type B | Peptide Substrate Type E | Peptide Substrate Type F |
|---|---|---|---|---|---|
| C. botulinum (A) | A219-A76 | + | − | − | − |
| C .botulinum (B) | 12-000-19474 | − | + | − | − |
| C .botulinum (E) | 1987-818 | − | − | + | − |
| C. botulinum (F) | ATCC 35415 | − | − | − | + |
| C. botulinum (A and B) 1 | WC | + | + | − | − |
|
C. botulinum (E) (Non-toxigenic) |
BAC-08-38772 | − | − | − | − |
| C. baratii (F) | BAC-07-4010 | − | − | − | + |
|
C. baratii (Non-toxigenic) |
ATCC 7659 | − | − | − | − |
| C. difficile | 2014-30621 | − | − | − | − |
| C. sporogenes | CDC 1967 | − | − | − | − |
| C. novyi | CDC 1976 | − | − | − | − |
| C. subterminale | 2012-39165 | − | − | − | − |
| C. perfringens | ATCC 13124 | − | − | − | − |
| C. butyricum | 1972-B1612 | − | − | − | − |
| C. tetani | CDC 14339 | − | − | − | − |
| Shiga Toxin Producing E.coli (O157:H7) |
ATCC 700728 | − | − | − | − |
| V.parahaemolyticus | ATCC 49529 | − | − | − | − |
| Ricin A Chain | Vector Labs | − | − | − | − |
|
S. aureus Enterotoxin B |
Toxin Technologies | − | − | − | − |
| C. jejuni | ATCC 33560 | − | − | − | − |
1 Wadsworth Center (WC) specimen was spiked with two toxins, BoNT/A and /B.