Table 1. Docking energy of test compounds to chain A and chain D of NMDA receptor, with the agonist compounds as reference.
Compounds | Chain A Energy (kcal/mol) | Chain D Energy (kcal/mol) |
---|---|---|
DDBM | −63. 0 ± 2.8 | −31.7 ± 5.0 |
HBPQ | −56.6 ± 4.6 | −41.0 ± 6.3 |
*ACPC | −65.2 ± 3.7 | — |
**t-ACBD | — | −53.6 ± 2.8 |
*Reference compound binds to chain A, 1-aminocyclopropane-1-carboxylic.
**Reference compound binds to chain D, trans-1-aminocyclobutane-1,3-dicarboxylic acid.