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. 2017 Mar 30;7:45540. doi: 10.1038/srep45540

Table 2. Docking energy of DDBM compound to NMDA receptor (chain A and chain D), GABA receptor and AMPA receptor.

Receptors Binding energy of DDBM Binding energy of the reference
(kcal/mol) (kcal/mol)
NMDA −63.0 ± 2.8 −65.2 ± 3.7
Chain A   1-aminocyclopropane-1-carboxylic acid
NMDA −31.7 ± 5.0 −53.6 ± 2.8
Chain D   trans-1-aminocyclobutane-1,3-dicarboxylic acid
GABA −21.0 ± 1.3 −1.6 ± 1.5
    Benzamidine
AMPA −18.4 ± 4.7 −29.8 ± 8.5
    Perampanel