Table 1. Carbamazepine-induced Stevens-Johnson syndrome (CBZ-SJS) cases and tolerant controls without HLA-B*15:02.
| Study (Region) | CBZ-SJS cases |
Tolerant controls |
|||
|---|---|---|---|---|---|
| Total | Cases without HLA-B*15:02 | HLA-B genotype of cases without HLA-B*15:02a | Total | Controls without HLA- B*15:02 | |
| Tassaneeyakul, 2010 (Thailand)3 | 42 | 5 | (1) 18:01/56:04(2) 15:21/48:01(3) 27:06/56:01(4) 15:21/40:01(5) 15:11/46:01 | 42 | 37 |
| Cheung, 2013 (Hong Kong)4 | 26 | 2 | (1) 13:01/54:01(2) 13:01/15:01 | 135 | 119 |
| Khor, 2014 (Malaysia)5 | 5 | 3 | (1) 15:08/56:01(2) 15:01/41:01(3) 40:06/51:06 | 52 | 50 |
| Nguyen, 2015 (Vietnam)6 | 35 | 3 | (1) 13:01/46:01(2) 51:02/54:01(3) 38:02/51:02 | 25 | 19 |
| Total | 108 | 13 | 254 | 225 | |
The data was obtained from available studies in Asian populations with known associations between HLA-B*15:02 and CBZ-SJS.
aUnderlined alleles represented members of the HLA-B75 serotype.