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. 2017 Mar 20;7(3):e015276. doi: 10.1136/bmjopen-2016-015276

Table 7.

Comparison of current review with results of two previous reviews in terms of successful recruitment to target sample size and extensions to recruitment

Review McDonald et al3 Sully et al4 This study This study
Recruitment period 1994–2002 2002–2008 2009–2016 2004–2016
Number of trials in the study N=122 N=73 N=90 N=151
Recruited 100% of original target 38 of 122 (31%) 40 of 73 (55%) 45 of 90 (50%) 61 of 151 (40%)
Original target was revised 42 of 122 (34%) 14 of 73 (19%) 35 of 90 (39%) 52 of 151 (34%)
Original target revised upward 6 of 42 (14%) 5 of 14 (36%) 10 of 35 (29%) 11 of 52 (21%)
Original target revised downward 36 of 42 (86%) 9 of 14 (64%) 25 of 35 (71%) 41 of 52 (79%)
Recruited 80% of original target 67 of 122 (55%) 57 of 73 (78%) 65 of 90 (72%) 95 of 151 (63%)
Recruited 100% of revised target 19 of 42 (45%) 10 of 14 (71%) 26 of 35 (74%) 28 of 52 (54%)
Recruited 80% of revised target 34 of 42 (80%) 13 of 14 (93%) 31 of 35 (89%) 48 of 52 (92%)
Extended their recruitment 65 of 122 (54%) 33 of 73 (45%) 28 of 90 (31%) 49 of 151 (32%)