Ethanol (EtOH) and corticosterone (CORT) differentially modulate male (A) and female (B) lateral (CeL) and medial (CeM) central amygdala synaptic responses to basolateral amygdala (BLA) stimulation. (A) In males, EtOH reduces EPSPs, whether the sole drug treatment or following CORT treatment, in both CeL and CeM, while CORT has a reduced effect on eEPSPs relative to EtOH and to CORT’s effects in females. (B) In females, CORT significantly reduces CeL, but not CeM, eEPSPs, whereas EtOH has a reduced ability to inhibit eEPSPs in females vs. males that is blocked in the presence of CORT.