Table 3.
Variation of oxidant and antioxidant parameters
Control (mean ± SD) N = 20 | DPNC (mean ± SD) N = 40 | DPWC (mean ± SD) N = 30 | |
---|---|---|---|
MDA (µmol/mg of protein) | 0.28 ± 0.03 | 0.29 ± 0.02 | 0.32 ± 0.03 |
NO2 − (µmol) | 191.41 ± 11.54 | 216.07 ± 8.96 | 227.38 ± 10.15 |
TAC (µmol/mg of protein) | 210.48 ± 6.22 | 160.46 ± 7.65* | 171.35 ± 6.43* |
CAT (U/mg of protein) | 28.34 ± 2.67 | 37.37 ± 1.78* | 35.19 ± 2.37* |
SOD (U/mg of protein) | 0.41 ± 0.04 | 0.38 ± 0.03* | 0.24 ± 0.01* |
GSH (µM/mg of protein) | 6.77 ± 0.59 | 9.78 ± 0.58* | 9.79 ± 0.73* |
LPI (MDA/TAC) | 0.180 | 0.181 | 0.186 |
Results are expressed as mean ± SD
DPNP diabetic patients without complications, DPWC diabetic patients with complications, LPI lipid peroxidation index, MDA malondialdehyde, CAT catalase, SOD: superoxide dismutase, GSH reduced glutathione, NO 2 nitrite oxide
* P < 0.05 significant compare with the control