Table 1.

Total proteins detected in LC-MS of serum and tissue purified histories of normal and tumour samples

Proteins	Tissue normal	Tissue tumour	Serum normal	Serum tumour
Histones	H2A type 1 (91.5%) H2A type 2-A (91.5%) H2A type 1-C (91.5%) H2A type 1-F (86.1%) H2B type 1E (91.5%) H2B type 1C (91.5%) H3.1 (99.2%) H4 (59.2%)	H2A type 2-A (98.4%) H2A type 1-C (98.4%) H2B type 1E (98%) H3.1 (99.2%) H4 (98.4%)	H2A type 2-A (81.5%) H2A type 1 (74.62%) H2A type 1-C (50%) H3.1 (59.2%) H2B type 1E (57%) H4 (60%)	H2A type 2-A (46.9%) H2A type 1-C (33%) H2A type 1-F (38.4%) H2A type 1-E (30%) H2A type 1 (33%) H2A type 4 (33%) H2B type 1E (57%) H2B type 1C (35%) H3.1 (40.7%) H4 (47%)
Non-histones	Prelamin A/C (26%) KDM5D (274%) ESF1 (30.6%) ESF1 homolog (23.9%) Acid-sensing ion channel 5 (12.9%)	Prelamin A/C (62.4%) KDM5D (30.32%) EIF2S3Y (29.8%) ESF1 homolog (41%) Acid-sensing ion channel (17.9%) Ribonuclease UK114	Fibrinogen beta chain (65.75%) Fibrinogen alpha chain (56.91%) Isoform 2 of Fibrinogen alpha (69.45%) Isoform 2 of Fibrinogen beta chain (70.96%) Translation initiation factor elf-2B (46.1%) Fertuin-B (47.6%) Putative pheromone receptor (18.7%)	Fibrinogen beta chain (65.3%) Fibrinogen alpha chain (43.3%) Isoform 2 of Fibrinogen beta chain (67.4%) Isoform 2 of Fibrinogen alpha chain (59.6%) Matrix estracellular phosphoglycoprotein (60%) Potassium voltage-gated channel subfamily C member 2 (30.8%) ESF1 homolog (57.9%) Alkaline phosphatase (57%) Indoleamine 2.3-dioxygenase 1 (37.8%) Aldehyde oxidase 2 (29.6%) Astrocytic phosphoprotein (69.9%) Transcription factor YY2 (32.9%) Cannabinoid receptor 1 (11.1%) Putative pheromone receptor (19.1%)