Table 1.
Demographic and clinical characteristics of the study population
| Total n = 227 |
MDA n = 133 |
No MDA n = 94 |
p | |
|---|---|---|---|---|
| Male, n (%) | 123 (54.2) | 82 (61.7) | 41 (43.6) | <0.05 |
| Age, mean (SD), years | 53.2 (12.4) | 53.5 (13.3) | 52.8 (10.9) | NS |
| Smoker, n (%) | 41 (18.1) | 19 (14.3) | 22 (23.4) | NS |
| Comorbidities, n (%) | ||||
| Dyslipemia | 69 (30.4) | 44 (33.1) | 25 (26.6) | NS |
| HBP | 62 (27.3) | 35 (26.3) | 27 (28.7) | NS |
| Obesity | 48 (21.1) | 32 (24.1) | 16 (17.0) | NS |
| DM | 23 (10.1) | 15 (11.3) | 8 (8.5) | NS |
| PsA characteristics | ||||
| PsA clinical pattern, n (%) | NS | |||
| Axial | 8 (3.5) | 3 (2.3) | 5 (5.3) | |
| Peripheral | 189 (83.3) | 113 (85.0) | 76 (80.9) | |
| Mixed | 30 (13.2) | 17 (12.8) | 13 (13.8) | |
| Familial history, n (%) | ||||
| Psoriasis | 112 (49.3) | 64 (48.1) | 48 (51.1) | NS |
| PsA | 28 (12.3) | 10 (7.5) | 18 (19.1) | <0.05 |
| Ankylosing spondylitis | 2 (0.9) | 2 (1.5) | 0 (0.0) | NS |
| PsA duration, mean (SD), years | 9.6 (7.7) | 9.80 (8.1) | 9.38 (7.3) | NS |
| Skin symptoms duration, mean (SD), years | 22.1 (14.7) | 20.6 (14.3) | 24.2 (15.1) | NS |
| Articular symptoms duration, mean (SD), years | 12.1 (9.3) | 11.8 (8.8) | 12.7 (9.9) | NS |
| PsA status at study visit | ||||
| Radiologic findings | ||||
| Erosions in hands, n (%) | 83 (36.6) | 41 (30.8) | 42 (44.7) | <0.05 |
| Joint in hands with erosion, mean (SD) | 4.3 (4.2) | 4.9 (4.5) | 3.7 (3.9) | NS |
| Erosions in feet, n (%) | 67 (29.5) | 38 (28.6) | 29 (30.9) | NS |
| Joint in feet with erosion, mean (SD) | 3.7 (3.4) | 3.9 (3.3) | 3.5 (3.7) | NS |
| PsAID, mean (SD) | 4.9 (4.5) | 3.3 (3.1) | 7.1 (5.2)) | <0.001 |
| PASI, mean (SD) | 1.6 (3.8) | 0.9 (1.6) | 2.8 (5.7) | <0.05 |
| BASDAI*, mean (SD) | 2.8 (2.4) | 2.0 (1.8) | 3.6 (2.5) | <0.001 |
| HAQ, mean (SD) | 0.8 (0.6) | 0.3 (0.5) | 0.5 (0.6) | <0.001 |
BASDAI Bath Ankylosing Spondylitis Disease Activity Index, DM diabetes mellitus, HAQ Health Assessment Questionnaire, HBP high blood pressure, MDA minimal disease activity, NS not significant, PASI Psoriasis Area and Severity Index, PsA psoriatic arthritis, PsAID Psoriatic Arthritis Impact of Disease, SD standard deviation. *Performed only in subjects with axial disease