Table 3.
Description of characteristics evaluated according to the type of HCV genotype (non-3 and 3) and the results of statistical tests
| Parameter | HCV genotype | P | ||
|---|---|---|---|---|
| Non-3 (n = 198) | 3 (n = 41) | Total | ||
| Age (years) | 0.231 | |||
| Mean ± SD | 55.2 ± 12.3 | 57.3 ± 9.7 | 55.5 ± 11.9 | |
| Median (min-max) | 57 (29–83) | 60 (31–71) | 57 (29–83) | |
| Gender, n (%) | 0.769 | |||
| Female | 116 (58.6) | 23 (56.1) | 139 (58.2) | |
| Male | 82 (41.4) | 18 (43.9) | 100 (41.8) | |
| Fibrosisa, n (%) | 0.307 | |||
| 0–2 | 159 (80.3) | 30 (73.2) | 189 (79.1) | |
| 3–4 | 39 (19.7) | 11 (26.8) | 50 (20.9) | |
| Siderosis, n (%) | 0.035 | |||
| Absent | 160 (80.8) | 27 (65.9) | 187 (78.2) | |
| Present | 38 (19.2) | 14 (34.1) | 52 (21.8) | |
| Inflammatory activitya, n (%) | 0.700 | |||
| 0–1 | 69 (34.8) | 13 (31.7) | 82 (34.3) | |
| 2–3 | 129 (65.2) | 28 (68.3) | 157 (65.7) | |
| ALT (U/L) | 0.242 | |||
| Mean ± SD | 60.1 ± 44.4 | 69.5 ± 55.8 | 61.7 ± 46.6 | |
| Median (min-max) | 47 (11–311) | 50 (19–296) | 47 (11–311) | |
| AST (U/L) | 0.487 | |||
| Mean ± SD | 49.3 ± 40 | 54 ± 34.9 | 50.1 ± 39.2 | |
| Median (min-max) | 37 (13–251) | 46 (21–163) | 38 (13–251) | |
| GGT (U/L) | 0.670 | |||
| Mean ± SD | 89.9 ± 99.6 | 82.4 ± 113.8 | 88.6 ± 102 | |
| Median (min-max) | 56 (8–733) | 41 (13–628) | 50 (8–733) | |
| Cholesterol (mg/dL) | 0.007 | |||
| Mean ± SD | 176 ± 41.4 | 157 ± 36.4 | 172.7 ± 41.2 | |
| Median (min-max) | 174.5 (69–399) | 160 (81–244) | 170 (69–399) | |
| LDL (mg/dL) | 0.024 | |||
| Mean ± SD | 97.9 ± 36.8 | 84 ± 28.5 | 95.5 ± 35.8 | |
| Median (min-max) | 97.5 (12–276) | 81 (34–157) | 93 (12–276) | |
| HDL (mg/dL) | 0.232 | |||
| Mean ± SD | 55.8 ± 18 | 52.2 ± 14.6 | 55.2 ± 17.5 | |
| Median (min-max) | 55.5 (21–110) | 50 (26–89) | 54 (21–110) | |
| VLDL (mg/dL) | 0.478 | |||
| Mean ± SD | 22.3 ± 13.2 | 20.8 ± 10.8 | 22.1 ± 12.8 | |
| Median (min-max) | 19 (5–105) | 17 (7–50) | 19 (5–105) | |
| Triglyceride (mg/dL) | 0.261 | |||
| Mean ± SD | 109.5 ± 63.4 | 97.7 ± 48.9 | 107.5 ± 61.2 | |
| Median (min-max) | 95 (34–502) | 84 (36–250) | 94 (34–502) | |
| BMI | 0.891 | |||
| Mean ± SD | 26.6 ± 4.3 | 26.5 ± 4.2 | 26.6 ± 4.2 | |
| Median (min-max) | 26.0 (17.4–39.2) | 25.7 (18.5–40.2) | 25.9 (17.4–40.2) | |
| HOMA-IR, n (%) | 0.771 | |||
| < 3 | 124 (64.9) | 25 (62.5) | 149 (64.5) | |
| ≥ 3 | 67 (35.1) | 15 (37.5) | 82 (35.5) | |
| MTTP, n (%) | 0.183 | |||
| GG | 95 (48) | 15 (36.6) | 110 (46) | |
| GT/TT | 103 (52) | 26 (63.4) | 129 (54) | |
Associations with qualitative variables were verified with the χ2 test, and comparisons of quantitative variables were performed with Student’s t-test, significance level of P < 0.10
aMetavir score