Table 1.
Study groups – demographic and clinical characteristics
| microalbuminuric | non-microalbuminuric | p | |
|---|---|---|---|
| Cases (male/female) | 11 (6/5) | 14 (6/8) | 0.57 |
| DM duration (years) | 26 (20–30) | 22.5 (21–25) | 0.78 |
| Age (years) | 35 (33–44) | 35 (32–40) | 0.76 |
| BMI (kg/m2) | 25.35 (21.97–28.6) | 24.15 (23.51–24.96) | 0.41 |
| Systolic BP (mmHg) | 138 (118–154) | 138 (124–143) | 1 |
| Diastolic BP (mmHg) | 84 (77–88) | 79.5 (74–90) | 0.62 |
| Serum creatinine (μmol/l) | 87 (81–116) | 71.5 (61–76) | <0.01 |
| eGFR (ml/min)a | 77.8 (63.6–100.4) | 108.8 (101.5–113.1) | <0.01 |
| Albumin/creatinine ratio (mg/mmol)b | 12.17 (5,56–15.15) | 0.505 (0.43–0.7) | <0.0001 |
| HbA1c | 7.9% (6.9–8.5) 63 mmol/mol (52–69) |
6% (5.3–7.1) 42 mmol/mol (34–54) |
<0.01 |
| Serum cholesterol (mmol/l) | 4.6 (4.1–5.4) | 5.4 (4.5–5.7) | 0.13 |
| Triglycerides (mmol/l) | 1.21 (1.09–1.34) | 0.88 (0.72–1.97) | 0.38 |
Data are given as medians (IQR), statistical significance was confirmed with Mann–Whitney rank sum test
aeGFR was calculated by CKD-EPI formula
bIn 9 non-microalbuminuric patients, urinary albumin was under the detection limit (<3 mg/l), here the albumin concentration was set arbitrarily to 3 mg/l