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. 2017 Mar 30;7:45580. doi: 10.1038/srep45580

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) PLS-DA scores plots derived from ¹H NMR data of biofluid samples (urine and serum) and tissue samples (extracted from stomach, cortex and medulla). (b) Heat-map for metabolite changes color-scaled with the contents of metabolites. The warm color denotes an increase of metabolite levels whereas cold color indicates a decrease in the treated rats with respect to the control group.