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. 2017 Mar 30;7:45647. doi: 10.1038/srep45647

Table 2. Steady-state and dissociation model parameters obtained from the analysis of HRC4 interaction with POPC, POPC:Chol (2:1) and POPC:Chol:SM (1:1:1) membranes.

Lipid Mixture Steady-state Model (±s.d.) Dissociation Model (±s.d.)
Kp × 103 σ koff,α × 10−3 (s−1) α koff,β × 10−3 (s−1) β <koff> × 10−3 (s−1) SL,r
POPC 2.54 (±0.29) 25.9 (±8.8) 3.8 (±0.3) 0.74 (±0.01) 26.0 (±2.0) 0.19 (±0.01) 8.30 (±0.8) 0.07 (±0.01)
POPC:Chol (2:1) 11.4 (±3.41) 41.4 (±2.7) 1.6 (±0.1) 0.64 (±0.05) 16.2 (±0.1) 0.16 (±0.01) 5.56 (±0.5) 0.20 (±0.05)
POPC:Chol:SM (1:1:1) 7.24 (±0.74) 48.7 (±3.6) 2.0 (±0.3) 0.70 (±0.02) 17.1 (±2.3) 0.16 (±0.02) 4.78 (±0.9) 0.14 (±0.01)