Table 3.
Expression of autophagy-related proteins in follicular neoplasms.
| Parameters | Total n = 265 (%) | FA n = 153 (%) | FC n = 112 (%) | p-Value |
|---|---|---|---|---|
| LC3A (T) | 0.300 | |||
| Negative | 240 (90.6) | 141 (92.2) | 99 (88.4) | |
| Positive | 25 (9.4) | 12 (7.8) | 13 (11.6) | |
| LC3A (S) | 0.278 | |||
| Negative | 227 (85.7) | 128 (83.7) | 99 (88.4) | |
| Positive | 38 (14.3) | 25 (16.3) | 13 (11.6) | |
| LC3B | 0.221 | |||
| Negative | 226 (85.3) | 127 (83.0) | 99 (88.4) | |
| Positive | 39 (14.7) | 26 (17.0) | 13 (11.6) | |
| p62 | 0.185 | |||
| Negative | 138 (52.1) | 85 (55.6) | 53 (47.3) | |
| Positive | 127 (47.9) | 68 (44.4) | 59 (52.7) | |
| BNIP-3 | 0.946 | |||
| Negative | 237 (89.7) | 137 (89.5) | 100 (89.3) | |
| Positive | 28 (10.6) | 16 (10.5) | 12 (10.7) |
FA: follicular adenoma; FC: follicular carcinoma; T: tumoral; S: stromal.