Table 6.
Univariate analysis of the influences of autophagy-related protein expression on disease-free and overall survival among patients with papillary thyroid cancer (log-rank test).
| Parameter | Number of Patients /Recurrence/Death | Disease-Free Survival | Overall Survival | ||
|---|---|---|---|---|---|
| Mean Survival (95% CI) Months | p-Value | Mean Survival (95% CI) Months | p-Value | ||
| LC3A (T) | 0.717 | 0.327 | |||
| Negative | 294/16/14 | 106 (104–109) | 108 (106–110) | ||
| Positive | 48/2/4 | 106 (100–111) | 103 (97–109) | ||
| LC3A (S) | 0.923 | 0.216 | |||
| Negative | 167/9/6 | 107 (103–110) | 109 (107–111) | ||
| Positive | 175/9/12 | 105 (102–108) | 104 (101–107) | ||
| LC3B | 0.257 | 0.805 | |||
| Negative | 146/10/7 | 105 (101–109) | 108 (105–111) | ||
| Positive | 196/8/11 | 108 (105–110) | 107 (105–110) | ||
| p62 | 0.643 | 0.140 | |||
| Negative | 134/8/4 | 105 (101–109) | 108 (106–111) | ||
| Positive | 208/10/14 | 107 (104–110) | 106 (103–109) | ||
| BNIP-3 | 0.804 | 0.055 | |||
| Negative | 297/16/13 | 106 (104–109) | 108 (106–110) | ||
| Positive | 45/2/5 | 107 (101–113) | 102 (95–110) | ||
CI: confidence interval; T: tumoral; S: stromal.