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ACE2 activity in serum and different tissues. (a) ACE2 activity in serum samples from CONT (open bars), DB (closed bars), and DB + INS (grey bars) mice at 21 and 40 days after diabetes onset; (b) ACE2 activity in lung, heart, liver, and pancreas from CONT, DB, and DB + INS. * p ≤ 0.05 CONT vs. DB; # p ≤ 0.05 DB vs. DB + INS; $ p ≤ 0.05 21 vs. 40 days of follow up.
