Table 2.

Multivariate analysis for the cognitive function treated with aripiprazole.

Variables	β	SE	F	t	P	R2
Verbal learning
Total explanatory power						0.55
First hospitalization age	0.04	0.02	2.58	1.61	0.12
The number of hospitalization	−0.55	0.23	5.66	−2.38	0.02
PANSS-N	−0.13	0.09	2.28	−1.51	0.14
PANSS-G	0.06	0.03	3.68	1.92	0.07
MHPG	0.39	0.18	4.68	2.16	0.04
BDNF	0.08	0.03	7.48	2.74	0.01
Working memory
Total explanatory power						0.48
Education	0.10	0.19	1.77	1.33	0.19
Total hospitalization period	−0.15	−0.36	6.23	−2.50	0.02
PANSS-N	−0.12	−0.22	2.65	−1.63	0.11
MHPG	0.53	0.42	10.39	3.22	0.00
Motor function
Total explanatory power						0.36
Education	0.21	0.09	5.93	2.44	0.02
First hospitalization age	−0.06	0.02	8.04	−2.84	0.01
MHPG	0.34	0.21	2.64	1.63	0.11
Verbal fluency
Total explanatory power						0.71
The number of hospital admissions	−0.46	0.15	8.96	−2.99	0.01
PANSS-N	−0.17	0.06	8.43	−2.90	0.01
DIEPSS	0.27	0.10	7.51	2.74	0.01
MHPG	0.53	0.13	15.69	3.96	0.00
BDNF	0.06	0.02	8.28	2.88	0.01
Attention and processing speed
Total explanatory power						0.76
Duration of illness	0.06	0.02	5.45	2.34	0.03
The number of hospitalization	−0.57	0.12	21.82	−4.67	0.00
PANSS-N	−0.10	0.05	3.93	−1.98	0.06
HVA	−0.33	0.10	11.80	−3.44	0.00
MHPG	0.76	0.11	45.87	6.77	0.00
Executive function
Total explanatory power						0.36
Education	0.16	0.12	1.75	1.32	0.20
Duration of illness	0.10	0.06	2.60	1.61	0.12
MHPG	0.86	0.29	8.75	2.96	0.01
BDNF	0.10	0.04	6.56	2.56	0.02

MHPG: 3-Methoxy-4-hydroxyphenylglycol; BDNF: Brain-derived neurotrophic factor; DIEPSS: Drug-induced extrapyramidal symptoms scale; HVA: Homovanillic acid. β: Regression coefficient; SE: Standard error; F: Variance ratio; t: t-Values; P: P-value; R²: Coefficient of determination.